Evidence map›Paper›PMID 32215836›Full record

ArticleMetabolic brain disease2020

Neuroprotective effects of boron nitride nanoparticles in the experimental Parkinson's disease model against MPP+ induced apoptosis.

Recep Küçükdoğru, Hasan Türkez, Mehmet Enes Arslan, Özlem Özdemir Tozlu, Erdal Sönmez, Adil Mardinoğlu, Ivana Cacciatore, Antonio Di Stefano

Abstract read
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In one paragraph

Article in Metabolic brain disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Review
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  6. Article
  7. Stimuli-Responsive Boron-Based Materials in Drug Delivery.International journal of molecular sciences · 2023
    Review
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  14. Review
  15. Interactions of a boron-containing levodopa derivative on DJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Recep KüçükdoğruDepartment of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, 25240, Türkiye.
Hasan TürkezDepartment of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, 25240, Türkiye.
Mehmet Enes ArslanDepartment of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, 25240, Türkiye. enes.aslan@erzurum.edu.tr.
Özlem Özdemir TozluDepartment of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, 25240, Türkiye.
Erdal SönmezDepartment of Physics, Kazım Karabekir Education Faculty, Atatürk University, Erzurum, Turkey.
Adil MardinoğluCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, SE1 9RT, UK.
Ivana CacciatoreDepartment of Pharmacology, G. D'Annunzio University, Chieti, Italy.
Antonio Di StefanoDepartment of Pharmacology, G. D'Annunzio University, Chieti, Italy.
Atatürk University · TRUniversity of Chieti-Pescara · ITKTH Royal Institute of Technology · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is one of the most aggressive neurodegenerative diseases and characterized by the loss of dopamine-sensitive neurons in the substantia nigra region of the brain. There is no any definitive treatment to completely cure PD and existing treatments can only ease the symptoms of the disease. Boron nitride nanoparticles have been extensively studied in nano-biological studies and researches showed that it can be a promising candidate for PD treatment with its biologically active unique properties. In the present study, it was aimed to investigate ameliorative effects of hexagonal boron nitride nanoparticles (hBNs) against toxicity of 1-methyl-4-phenylpyridinium (MPP

Indexed as

1-Methyl-4-phenylpyridiniumApoptosisBoron CompoundsCell Line, TumorCell SurvivalDose-Response Relationship, DrugHumansNanoparticlesNeuroprotective AgentsParkinsonian Disorders1-Methyl-4-phenylpyridiniumBoron Compoundsboron nitrideNeuroprotective Agents1-methyl-4-phenylpyridiniumExperimental Parkinson’s disease modelHexagonal boron nitride nanoparticlesIn vitroNeuroprotective agentParkinson’s disease

Identifiers

PMID32215836
OpenAlexW3013504813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.