Evidence map›Paper›PMID 32215452›Full record

ArticleJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

Mechanical ventilation weaning practices in neonatal and pediatric ICUs in Brazil: the Weaning Survey-Brazil.

Suzi Laine Longo Dos Santos Bacci, Cíntia Johnston, Wallisen Tadashi Hattori, Janser Moura Pereira, Vívian Mara Gonçalves de Oliveira Azevedo

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06401083 (The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06401083 phase4recruitingnot on this map

The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate

TypeinterventionalSponsorSemmelweis UniversityRan2023 to 2028Enrolled226ConditionsApnea of Prematurity, Premature Birth, Respiratory FailureArmsCaffeine citrate
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Qualineo Strategy Indicators Associated with Neonatal Death: A Cross-Sectional Study.International journal of environmental research and public health · 2024
    Article
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Suzi Laine Longo Dos Santos Bacci. Programa de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Uberlândia, Uberlândia (MG) Brasil.ORCID http://orcid.org/0000-0001-7375-8742
Cíntia Johnston. Departamento de Pediatria, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.ORCID http://orcid.org/0000-0002-1504-9160
Wallisen Tadashi Hattori. Departamento de Saúde Coletiva, Faculdade de Medicina, Universidade Federal de Uberlândia, Uberlândia (MG) Brasil.ORCID http://orcid.org/0000-0002-6904-0292
Janser Moura Pereira. Faculdade de Matemática, Universidade Federal de Uberlândia, Uberlândia (MG) Brasil.ORCID http://orcid.org/0000-0002-4622-6203
Vívian Mara Gonçalves de Oliveira Azevedo. Programa de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Uberlândia, Uberlândia (MG) Brasil.ORCID http://orcid.org/0000-0002-7514-1508
Universidade Federal de Uberlândia · BRDean College · USUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to describe practices for weaning from mechanical ventilation (MV), in terms of the use of protocols, methods, and criteria, in pediatric ICUs (PICUs), neonatal ICUs (NICUs), and mixed neonatal/pediatric ICUs (NPICUs) in Brazil.

methodsThis was a cross-sectional survey carried out by sending an electronic questionnaire to a total of 298 NICUs, PICUs, and NPICUs throughout Brazil.

resultsCompleted questionnaires were assessed for 146 hospitals, NICUs accounting for 49.3% of the questionnaires received, whereas PICUs and NPICUs accounted for 35.6% and 15.1%, respectively. Weaning protocols were applied in 57.5% of the units. In the NICUs and NPICUs that used weaning protocols, the method of MV weaning most commonly employed (in 60.5% and 50.0%, respectively) was standardized gradual withdrawal from ventilatory support, whereas that employed in most (53.0%) of the PICUs was spontaneous breathing trial (SBT). During the SBTs, the most common ventilation mode, in all ICUs, was pressure-support ventilation (10.03 ± 3.15 cmH2O) with positive end-expiratory pressure. The mean SBT duration was 35.76 ± 29.03 min in the NICUs, compared with 76.42 ± 41.09 min in the PICUs. The SBT parameters, weaning ventilation modes, and time frame considered for extubation failure were not found to be dependent on the age profile of the ICU population. The findings of the clinical evaluation and arterial blood gas analysis are frequently used as criteria to assess readiness for extubation, regardless of the age group served by the ICU.

conclusionsIn Brazil, the clinical practices for weaning from MV and extubation appear to vary depending on the age group served by the ICU. It seems that weaning protocols and SBTs are used mainly in PICUs, whereas gradual withdrawal from ventilatory support is more widely used in NICUs and NPICUs.

Indexed as

BrazilChildCross-Sectional StudiesHealth Care SurveysHumansInfant, NewbornIntensive Care Units, PediatricRespiration, ArtificialRespiratory InsufficiencySurveys and QuestionnairesVentilator Weaning

Identifiers

PMID32215452
PMCPMC7567621
OpenAlexW3006828053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.