Evidence map›Paper›PMID 32215349›Full record

ArticleJACC. Basic to translational science2020

Selective Autoretroperfusion Provides Substantial Cardioprotection in Swine: Incremental Improvements With Mild Hypothermia.

Jenny S Choy, Zachary C Berwick, Brandon D Kalasho, Lijuan Fu, Deepak L Bhatt, Jose A Navia, Ghassan S Kassab

Open access · goldAbstract read
In one paragraph

Article in JACC. Basic to translational science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Preconditioning with selective autoretroperfusion:Frontiers in bioengineering and biotechnology · 2024
    Article
  3. Review
  4. Cardioprotection, Autoretroperfusion, and Therapeutic Hypothermia.JACC. Basic to translational science · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jenny S ChoyCalifornia Medical Innovations Institute, San Diego, California.
Zachary C Berwick3DT Holdings, San Diego, California.
Brandon D Kalasho3DT Holdings, San Diego, California.
Lijuan FuCalifornia Medical Innovations Institute, San Diego, California.
Deepak L BhattBrigham and Women's Hospital Heart & Vascular Center, Harvard Medical School, Boston, Massachusetts.
Jose A NaviaDepartment of Surgery, Austral University, Buenos Aires, Argentina.
Ghassan S KassabCalifornia Medical Innovations Institute, San Diego, California.
California Medical Innovations Institute · USAustral University · ARBrigham and Women's Hospital · US

Funding

Mild Hypothermia Catheter for Reperfusion InjuryR44HL120375 · NHLBI · 3DT HOLDINGS, LLC · PI HUBBARD, TERRY, KASSAB, GHASSAN S · 2017 to 2018
$2.0M
NHLBI NIH HHS R44 HL120375
6 · The paper itself

Abstract

Mild hypothermia (MH) and retroperfusion are 2 techniques proposed to reduce infarct size due to myocardial infarction. The authors evaluated the effects of focal MH combined with selective coronary venous autoretroperfusion (SARP) as an acute cardioprotective modality before percutaneous coronary intervention (PCI) in a swine model of left ventricular myocardial infarction. Significant reduction in infarct size with preservation of cardiac function and cardiomyocyte viability were achieved. The authors propose that SARP alone or in combination with MH may provide a clinically relevant percutaneous short-term option of cardiac support to high-risk patients undergoing PCI.

Indexed as

acute myocardial infarctionAMI, acute myocardial infarctioncardioprotectioncTnI, cardiac troponin IEF, ejection fractionfocal mild-hypothermiaGCV, great cardiac veinIABP, intra-aortic balloon pumpLAD, left anterior descending coronary arteryLV, left ventricle/ventricularMH, mild hypothermiamiR, microRNAPCI, percutaneous coronary interventionPO2, partial pressure of oxygenSARP, selective autoretroperfusionselective autoretroperfusionSTEMI, ST-segment elevation myocardial infarction

Identifiers

PMID32215349
PMCPMC7091507
OpenAlexW3006197721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.