Evidence map›Paper›PMID 32215253›Full record

ArticleMetabolic engineering communications2020

Synthetic control of plasmid replication enables target- and self-curing of vectors and expedites genome engineering of

Daniel C Volke, Laura Friis, Nicolas T Wirth, Justine Turlin, Pablo I Nikel

Open access · goldAbstract read
In one paragraph

Article in Metabolic engineering communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 106 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Adaptive evolution ofJournal of bacteriology · 2026
    Article
  6. Functional organization and regulatory logic of theApplied and environmental microbiology · 2026
    Review
  7. Article
  8. Review
  9. Genome-ReducedEngineering in life sciences · 2025
    Article
  10. Synthetic CmBio · 2025
    Article
  11. Article
  12. Article
  13. Precision engineering of the probioticApplied and environmental microbiology · 2025
    Article
  14. Article
  15. Construction of a syntrophicSynthetic biology (Oxford, England) · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daniel C VolkeThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800, Kgs Lyngby, Denmark.
Laura FriisThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800, Kgs Lyngby, Denmark.
Nicolas T WirthThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800, Kgs Lyngby, Denmark.
Justine TurlinThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800, Kgs Lyngby, Denmark.
Pablo I NikelThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800, Kgs Lyngby, Denmark.
Technical University of Denmark · DKNovo Nordisk Foundation · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome engineering of non-conventional microorganisms calls for the development of dedicated synthetic biology tools.

Indexed as

Genome engineeringMetabolic engineeringPlasmid curingPseudomonas putidaSynthetic biology

Identifiers

PMID32215253
PMCPMC7090339
OpenAlexW3010972153

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.