Evidence map›Paper›PMID 32215174›Full record

ArticleOxidative medicine and cellular longevity2020

miR-155-5p Promotes Oxalate- and Calcium-Induced Kidney Oxidative Stress Injury by Suppressing MGP Expression.

Kehua Jiang, Jianxin Hu, Guangheng Luo, Dalong Song, Peng Zhang, Jianguo Zhu, Fa Sun

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
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  4. Article
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  7. Noncoding RNA, friend or foe for nephrolithiasis?Frontiers in cell and developmental biology · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Review
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  13. Article
  14. Annals of translational medicine · 2021
    Article
  15. Article
  16. Effect of autophagy on oxalate-induced toxicity of human proximal renal tubular epithelial cell.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Article
  17. Article
  18. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kehua JiangDepartment of Urology, Guizhou Provincial People's Hospital, Guiyang, China.ORCID https://orcid.org/0000-0002-9446-3158
Jianxin HuDepartment of Urology, Guizhou Provincial People's Hospital, Guiyang, China.ORCID https://orcid.org/0000-0002-5095-9063
Guangheng LuoDepartment of Urology, Guizhou Provincial People's Hospital, Guiyang, China.ORCID https://orcid.org/0000-0003-1648-5973
Dalong SongDepartment of Urology, Guizhou Provincial People's Hospital, Guiyang, China.ORCID https://orcid.org/0000-0002-9771-9577
Peng ZhangDepartment of Urology, Guizhou Provincial People's Hospital, Guiyang, China.ORCID https://orcid.org/0000-0003-2569-7257
Jianguo ZhuDepartment of Urology, Guizhou Provincial People's Hospital, Guiyang, China.ORCID https://orcid.org/0000-0002-4037-0394
Fa SunDepartment of Urology, Guizhou Provincial People's Hospital, Guiyang, China.ORCID https://orcid.org/0000-0003-3556-0131
Guizhou Provincial People's Hospital · CNGuizhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxalate and calcium are the major risk factors for calcium oxalate (CaOx) stone formation. However, the exact mechanism remains unclear. This study was designed to confirm the potential function of miR-155-5p in the formation of CaOx induced by oxalate and calcium oxalate monohydrate (COM). The HK-2 cells were treated by the different concentrations of oxalate and COM for 48 h. We found that oxalate and COM treatment significantly increased ROS generation, LDH release, cellular MDA levels, and H

Indexed as

Oxidative Stress3' Untranslated RegionsAnimalsCalcium-Binding ProteinsCalcium OxalateCell Line, TransformedExtracellular Matrix ProteinsGene Expression RegulationHumansKidneyMaleMatrix Gla ProteinMiceMice, Inbred C57BLMicroRNAsOxalates3' Untranslated RegionsCalcium-Binding ProteinsCalcium OxalateExtracellular Matrix ProteinsMatrix Gla ProteinMicroRNAsMIRN155 microRNA, humanOxalates

Identifiers

PMID32215174
PMCPMC7081043
OpenAlexW3009373487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.