Evidence map›Paper›PMID 32215173›Full record

ReviewOxidative medicine and cellular longevity2020

What and How Can Physical Activity Prevention Function on Parkinson's Disease?

Baozhu Fan, Riffat Jabeen, Bing Bo, Chunlei Guo, Mengjie Han, Hui Zhang, Juan Cen, Xinying Ji, Jianshe Wei

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 7 pooled it
3.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 7 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Baozhu FanLaboratory of Brain Function and Disease, Institute for Brain Sciences Research, School of Life Sciences, Henan University, China.
Riffat JabeenLaboratory of Brain Function and Disease, Institute for Brain Sciences Research, School of Life Sciences, Henan University, China.
Bing BoLaboratory of Brain Function and Disease, Institute for Brain Sciences Research, School of Life Sciences, Henan University, China.
Chunlei GuoLaboratory of Brain Function and Disease, Institute for Brain Sciences Research, School of Life Sciences, Henan University, China.
Mengjie HanLaboratory of Brain Function and Disease, Institute for Brain Sciences Research, School of Life Sciences, Henan University, China.
Hui ZhangSchool of Physical Education, Henan University, Kaifeng, 475004 Henan, China.
Juan CenLaboratory of Brain Function and Disease, Institute for Brain Sciences Research, School of Life Sciences, Henan University, China.
Xinying JiHenan International Joint Laboratory of Nuclear Protein Regulation, Kaifeng 475004, China.ORCID https://orcid.org/0000-0003-0690-4206
Jianshe WeiLaboratory of Brain Function and Disease, Institute for Brain Sciences Research, School of Life Sciences, Henan University, China.ORCID https://orcid.org/0000-0002-3560-3392
Henan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study was aimed at investigating the effects and molecular mechanisms of physical activity intervention on Parkinson's disease (PD) and providing theoretical guidance for the prevention and treatment of PD.

methodsFour electronic databases up to December 2019 were searched (PubMed, Springer, Elsevier, and Wiley database), 176 articles were selected. Literature data were analyzed by the logic analysis method.

results(1) Risk factors of PD include dairy products, pesticides, traumatic brain injury, and obesity. Protective factors include alcohol, tobacco, coffee, black tea, and physical activity. (2) Physical activity can reduce the risk and improve symptoms of PD and the beneficial forms of physical activity, including running, dancing, traditional Chinese martial arts, yoga, and weight training. (3) Different forms of physical activity alleviate the symptoms of PD through different mechanisms, including reducing the accumulation of

conclusionPhysical activity has a positive impact on the prevention and treatment of PD. Illustrating the molecular mechanism of physical activity-induced protective effect on PD is an urgent need for improving the efficacy of PD therapy regimens in the future.

Indexed as

alpha-SynucleinBrain-Derived Neurotrophic FactorExerciseExercise TherapyHumansInflammationMitochondriaOxidative StressParkinson DiseaseRisk Factorsalpha-SynucleinBrain-Derived Neurotrophic Factor

Identifiers

PMID32215173
PMCPMC7042542
OpenAlexW3005602146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.