ReviewOxidative medicine and cellular longevity2020
Therapeutic Potential of Diosgenin and Its Major Derivatives against Neurological Diseases: Recent Advances.
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Review in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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0cells of the map it votes in
45citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
What it found
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Who cites it
45 citing papers in PubMed, 110 citations in OpenAlex.
- Role of Plant-Derived Antioxidants in Oxidative Stress-Associated Myocardial Infarction: Structure-Activity Relationship (SAR)-Based Mechanistic Insights.Molecules (Basel, Switzerland) · 2026Review
- Diosgenin-loaded niosomes ameliorate cadmium-induced neurotoxicity and endocrine disruption in female rats through modulation of oxidative stress, apoptosis, and inflammatory markers.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- A tri-target in silico analysis of Testolift: a nutraceutical formulation targeting aromatase, myostatin, and prolyl hydroxylase-2 in testosterone regulation and muscle performance.Scientific reports · 2026Article
- Transferrin-modified multicomponent liposomes encapsulating paclitaxel-loadedInternational journal of pharmaceutics: X · 2026Article
- Immunomodulatory and locomotor regulations via Diosgenin treatment in lipopolysaccharide-induced chronic fatigue syndrome (CFS)/ depressive despair symptom: an in vivo assessment.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Bibliometric mapping of glioma classification research through main path, key route, and K-core analyses.Oncotarget · 2026Review
- Discovery of a Neuroprotective Diosgenin Derivative as a Novel Antidepressant Candidate Targeting LPS-TLR4 Signaling.Journal of medicinal chemistry · 2026Article
- Diosgenin-mediated NF-κB and MAPK pathway modulation for osteoarthritis treatment: molecular mechanisms, bioavailability enhancement, and therapeutic applications.Inflammopharmacology · 2026Review
- Structural basis for diosgenin as an inverse agonist of retinoic acid receptor-related orphan receptor γ.Scientific reports · 2026Article
- Diosgenin mitigates laser-induced choroidal neovascularization by suppressing the endothelial-to-mesenchymal transition via the TGF-β/Smad and MAPKs signaling pathways.American journal of translational research · 2026Article
- Role of IGF1/IGFR signaling pathway in neuroprotective effect of Shengmai Dihuang Decoction on CIH-induced cognitive impairment.Journal of traditional and complementary medicine · 2026Article
- Natural Chiral Scaffolds in Alzheimer's Disease: Therapeutic Potential, Mechanism, and Clinical Aspects.BioMed research international · 2026Review
- The role of neuroactive steroids in psychiatric and neurological disorders: Neurobiology and therapeutic perspectives.Neuroscience and biobehavioral reviews · 2025Review
- Isolation, biochemical characterization, and primary structure and active site determination ofBiochemistry and biophysics reports · 2025Article
- Diosgenin ameliorates silica-induced tuberculosis in rats.Animal models and experimental medicine · 2025Article
- Anti- Cancer Potential of Diosgenin, a Steroidal Saponin, against Human Oral Cancer Cells.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Exploring the molecular mechanism ofHeliyon · 2025Article
- Exploring the toxicity mechanisms and detoxification methods of Rhizoma Paridis.Open life sciences · 2025Review
- An Updated Review of Molecular Mechanisms Implicated with the Anticancer Potential of Diosgenin and Its Nanoformulations.Drug design, development and therapy · 2025Review
- Diosgenin protects against cationic bovine serum albumin-induced membranous glomerulonephritis by attenuating oxidative stress and renal inflammation via the NF-κB pathway.Pharmaceutical biology · 2024Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Bangrong CaiHenan Research Center for Special Processing Technology of Chinese Medicine, School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0002-9922-6389
Ying ZhangDepartment of Biochemistry, Department of Biomedical Sciences, Research Center for Aging and Geriatrics, Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju 501-190, Republic of Korea.ORCID https://orcid.org/0000-0002-3672-3345
Zengtao WangDepartment of Medicinal Chemistry, College of Pharmacy JiangXi University of Traditional Chinese Medicine, Nanchang 330004, China.
Dujuan XuHenan Research Center for Special Processing Technology of Chinese Medicine, School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Yongyan JiaHenan Research Center for Special Processing Technology of Chinese Medicine, School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Yanbin GuanHenan Research Center for Special Processing Technology of Chinese Medicine, School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Aimei LiaoCollege of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China.
Gaizhi LiuHenan Research Center for Special Processing Technology of Chinese Medicine, School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0002-5422-2931
ChangJu ChunResearch Institute of Drug Development, College of Pharmacy, Chonnam National University, Gwangju, Republic of Korea.ORCID https://orcid.org/0000-0002-2452-6184
Jiansheng LiCollaborative Innovation Center for Respiratory Disease Diagnosis and Treatment and Chinese Medicine Development of Henan Province, Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, China.ORCID https://orcid.org/0000-0002-2714-9353
First Affiliated Hospital of Henan University · CNChonnam National University · KRHenan University of Technology · CNJiangxi University of Traditional Chinese Medicine · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diosgenin (DG), a well-known steroidal sapogenin, is present abundantly in medicinal herbs such as
Indexed as
AnimalsBiological AvailabilityCognitionDiosgeninDisease Models, AnimalHumansMolecular StructureNervous System DiseasesNeuroprotective AgentsPlants, MedicinalDiosgeninNeuroprotective Agents
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.