Evidence map›Paper›PMID 32215125›Full record

ReviewPrzeglad gastroenterologiczny2020

Eosinophilic pancreatitis: a rare or unexplored disease entity?

Murli Manohar, Alok K Verma, Gulshan Singh, Anil Mishra

Open access · goldAbstract readReview
In one paragraph

Review in Przeglad gastroenterologiczny, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Murli ManoharDepartment of Medicine, Section of Pulmonary Diseases, Tulane Eosinophilic Disorders Centre, Tulane University School of Medicine, New Orleans, LA, USA.
Alok K VermaDepartment of Medicine, Section of Pulmonary Diseases, Tulane Eosinophilic Disorders Centre, Tulane University School of Medicine, New Orleans, LA, USA.
Gulshan SinghDepartment of Global Environmental Health Sciences, School of Public Health and Tropical Medicine, Tulane University School of Medicine, New Orleans, LA, USA.
Anil MishraDepartment of Medicine, Section of Pulmonary Diseases, Tulane Eosinophilic Disorders Centre, Tulane University School of Medicine, New Orleans, LA, USA.
Tulane University · US

Funding

Role of IL-15 in the Pathogensis of Eosinophilic EsophagitisR01AI080581 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI MISHRA, ANIL · 2009 to 2023
$4.9M
NIAID NIH HHS R01 AI080581
6 · The paper itself

Abstract

Several case reports show accumulation of eosinophils in pancreatitis patients and term the disease as "eosinophilic pancreatitis (EP)". EP usually presents with a pancreatic tumour and abdominal pain in obstructive jaundice, which is generally not diagnosed until the patient undergoes pancreatic resection. Histologically, EP reveals distinct patterns like diffused, periductal, acinar, and septal inflammatory infiltrates with eosinophils, eosinophilic phlebitis, and localised extreme eosinophilic infiltrates related with pseudocyst formation. EP patients also have elevated serum IgE levels with high eosinophil counts in the pancreas as well as in other organs such as the gastrointestinal tract, which is termed as eosinophilic gastroenteritis. Due to the lack of knowledge based on just a few case reports, it is considered that eosinophilic infiltration is quite rare in the pancreas; therefore, the significance of eosinophils in pancreatitis is not yet established. This review assesses the current understanding of eosinophilic pancreatitis and the important role of eosinophils in promoting pancreatic fibrosis including malignancy.

Indexed as

eosinophilic pancreatitiseosinophilshypereosinophilic syndromepancreatic neoplasiapancreatitis

Identifiers

PMID32215125
PMCPMC7089860
OpenAlexW3013482294

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.