Evidence map›Paper›PMID 32215087›Full record

ArticleOpen access Macedonian journal of medical sciences2019

Clinical Characteristics and Histopathology of Idiopathic Epiretinal Membrane in Vietnam.

Nguyen Dinh Ngan, Nguyen Van Cuong, Nguyen Le Trung, Dang Tran Dat, Hoang Anh Tuan, Pham Ngoc Dong, Vu Thi Nga, Nguyen Duy Bac, Cung Le Xuan

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Article in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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3 · Its place in the literature

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4 citing papers in PubMed.

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  4. Vitreomacular interface abnormalities in type 2 macular telangiectasia (MacTel).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Nguyen Dinh NganDepartment of Ophthalmology, 103 Military Hospital, Hanoi, Vietnam.
Nguyen Van CuongDepartment of Ophthalmology, 103 Military Hospital, Hanoi, Vietnam.
Nguyen Le TrungDepartment of Ophthalmology, 103 Military Hospital, Hanoi, Vietnam.
Dang Tran DatVietnam National Institute of Ophthalmology, Hanoi, Vietnam.
Hoang Anh TuanVietnam National Institute of Ophthalmology, Hanoi, Vietnam.
Pham Ngoc DongVietnam National Institute of Ophthalmology, Hanoi, Vietnam.
Vu Thi NgaInstitute for Research and Development, Duy Tan University, 03 Quang Trung, Danang, Vietnam.
Nguyen Duy BacVietnam Military Medical University (VMMU), Hanoi, Vietnam.
Cung Le XuanVietnam National Institute of Ophthalmology, Hanoi, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdiopathic epiretinal membrane (iERM) is an avascular proliferation of different types of cells between the posterior vitreous cortex and the internal limiting membrane. That causes visual impairment including blurry, distortion, scotoma. Many studies of iERM were done to describe the clinical characteristics and investigate the histopathology of this disease. Nonetheless, there has not been a study of iERM histopathology in Vietnam.

aimTo describe clinical characteristics and histopathological results of idiopathic retinal membrane and the association between them.

methodsA cross sectional decriptive study of 35 iERMs (33 patients) in Vietnam National Institute of Ophthalmology (VNIO).

resultsHigh morbidity incidence was in group age >50 years (32/35), female gender (26/35), limited movement works (27/35), and high educational levels (28/35). Distortion was the highest (77.14%), scotoma and floater was less frequent (28.5%, 45.7%). Macular edema in all cases and PVD and exudate were high frequent (65.7%, 62.8%). Symptom duration was 8.2 ± 4.7 months, (1-21 months). Mean of central macular thickness was 468.51 ± 97.24 µm (656-274 µm). Six types of cell were detected, including glial cell (35/35), fibroblast (23/35), myofibroblast (23/35), macrophage (13/35), lymphocyte (5/35) and neutrophil (2/35). The number of cell types in one sample ranged from 1-5 types (2.85 ± 1.28 cell types). Number of cell types were correlated to symptom duration (r = 0.47, p = 0.004, Pearson's test) and central macular thickness (r = 0.72, p < 0.001, Pearson's test).

conclusionThere were 6 types of cells in iERM. Glial cell was the most frequent cell, inflammatory cells (macrophage, lymphocyte, neutrophil) was also detected. The number of cell types was stastitically correlated to symptom duration and CMT.

Indexed as

HistopathologyIdiopathic epiretinal membraneiERM

Identifiers

PMID32215087
PMCPMC7084043

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