Evidence map›Paper›PMID 32215086›Full record

ArticleOpen access Macedonian journal of medical sciences2019

HMU Fluorinze Mouthwash Enhances Enamel Remineralization: An In Vitro Study.

Vo Truong Nhu Ngoc, Kimberly Mathieu Coulton, Nguyen Thu Tra, Nguyen Ha My, Phi Thi Quynh Huong, Tong Minh Son, Le Quynh Anh, Luu Quang Thuy, Tran Tuan Anh, Thien Chu Dinh and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Vo Truong Nhu NgocSchool of Odonto Stomatology, Hanoi Medical University, Hanoi, Vietnam.
Kimberly Mathieu CoultonSchool of Dentistry, Faculty of Medicine and Health, University of Sydney, Australia.
Nguyen Thu TraSchool of Odonto Stomatology, Hanoi Medical University, Hanoi, Vietnam.
Nguyen Ha MySchool of Odonto Stomatology, Hanoi Medical University, Hanoi, Vietnam.
Phi Thi Quynh HuongSchool of Odonto Stomatology, Hanoi Medical University, Hanoi, Vietnam.
Tong Minh SonSchool of Odonto Stomatology, Hanoi Medical University, Hanoi, Vietnam.
Le Quynh AnhSchool of Odonto Stomatology, Hanoi Medical University, Hanoi, Vietnam.
Luu Quang ThuyViet Duc Hospital, Hanoi, Vietnam.
Tran Tuan AnhBecamex International Hospital, Thuan An, Binh Duong, Vietnam.
Thien Chu DinhInstitute for Research and Development, Duy Tan University, 03 Quang Trung, Danang, Vietnam.
Chu Dinh ToiDepartment of Human and Animal Physiology, Faculty of Biology, Hanoi National University of Education, Hanoi, Vietnam.
Hanoi Medical University · VNDuy Tan University · VNHanoi National University of Education · VNUniversity of Sydney · AUViet Duc Hospital · VNVinmec International Hospital · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFluoride therapy has long been used extensively to prevent dental caries. Fluoride appears in a variety of dental care products such as mouth rinses, dentifrices, gels, etc. HMU Fluorinze is the first mouthwash containing fluoride in Vietnam.

aimThis research was conducted to evaluate the efficacy of HMU Fluorinze mouthwash on remineralizing enamel in laboratory conditions.

methods20 third molar teeth were cleaned and covered with nail polish, except for a 3 x 3 mm square on their buccal surfaces. These teeth underwent two steps: demineralization using Coca-cola and remineralization for 20 daysusing standard calcifying solution (control group) and standard calcifying solution + HMU Fluorinze mouthwash 2 times/day (experimental group). The index measured of enamel structure after demineralization and remineralization was assessed by a DIAGNOdent pen 2190.

resultsThe indices measured of the control group and experimental group at baseline were 3.65 ± 0.76 and 3.35 ± 0.64 respectively. After demineralization the control group measured 21.78 ± 4.48 and the experimental group, 20.25 ± 2.26. Following remineralization, the control group scores were 6.30 ± 1.03 and the experimental group, 3.90 ± 1.24, demonstrating statistical significance (p < 0.01) between the two groups. After 20 days, the results for the experimental group did not differ from the original results (p = 0.272), in contrast with the control group (p < 0.01).

conclusionResults show that HMU Fluorinze mouthwash is better at remineralizing than standard calcifying solution.

Indexed as

Enamel remineralizationHMU FluorinzeMouthwash

Identifiers

PMID32215086
PMCPMC7084033
OpenAlexW3009305556

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.