Evidence map›Paper›PMID 32215010›Full record

ArticleInternational journal of endocrinology2020

Parathyroid Carcinoma: An Up-to-Date Retrospective Multicentric Analysis.

Francesco Quaglino, Luca Manfrino, Luca Cestino, Massimo Giusti, Enrico Mazza, Alessandro Piovesan, Nicola Palestini, Corrado Lauro, Elena Castellano

Open access · goldAbstract read
In one paragraph

Article in International journal of endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Critical Insights into Parathyroid Cancer.Journal of cancer science and clinical therapeutics · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Association of preoperative risk factors with therapeutic outcomes in primary hyperparathyroidism: A multivariate analysis of imaging and PTH-Calcium-Phosphate metabolic parameters in 164 cases.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Immunohistochemical Profile of Parathyroid Tumours: A Comprehensive Review.International journal of molecular sciences · 2022
    Review
  13. A parathyroid carcinoma mimicking thyroid carcinoma; A case report.International journal of surgery case reports · 2022
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Francesco QuaglinoDepartment of General Surgery, "Maria Vittoria" Hospital ASL Città di Torino, Turin 10144, Italy.
Luca ManfrinoDepartment of General Surgery, "Maria Vittoria" Hospital ASL Città di Torino, Turin 10144, Italy.ORCID https://orcid.org/0000-0002-4230-1368
Luca CestinoDepartment of General Surgery, "Maria Vittoria" Hospital ASL Città di Torino, Turin 10144, Italy.
Massimo GiustiDepartment of Internal Medicine, "San Giovanni Bosco" Hospital ASL Città di Torino, Turin 10154, Italy.
Enrico MazzaDepartment of Endocrinology, "Maria Vittoria" Hospital ASL Città di Torino, Turin 10144, Italy.
Alessandro PiovesanDepartment of Endocrinology, A. O. U. Città della Salute della Scienza di Torino, Turin 10126, Italy.
Nicola PalestiniThyroid and Parathyroid Surgery, Candiolo Cancer Institute I. R. C. C. S., Candiolo 10060, Italy.
Corrado LauroDepartment of General Surgery, "Santa Croce e Carle" Hospital, Cuneo 12100, Italy.
Elena CastellanoDepartment of Endocrinology, Diabetes and Metabolism, "Santa Croce e Carle" Hospital, Cuneo 12100, Italy.
Ospedale Maria Vittoria · ITAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITCandiolo Cancer Institute · ITOspedale San Giovanni Bosco · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parathyroid carcinoma (PC) is a rare disease responsible for about 1% of primary hyperparathyroidism (PHPT) cases. PC usually has an indolent course, tough to differentiate from the benign causes of PHPT, and the only certain diagnosis is histologic. The gold standard surgical treatment is the en bloc resection associated with the homolateral thyroid loboistmectomy. The aim of this study was to underline the main differences between PC and benign PHPT, along with gathering epidemiological knowledge relative to PC in our region. Data from the regional cancer network (Rete Oncologica del Piemonte e della Valle d'Aosta) since 2007 have been reported, including 21 patients from three hospitals (AO S. Croce e Carle of Cuneo, AOU Città della Salute of Turin, and ASL Città di Torino). The incidence of the disease, gender, age at time of diagnosis, presence of renal and bone symptoms, serum calcium and PTH levels, surgical technique performed, and percentage of recurrence were analysed. PC data were than compared with a series of patients affected by benign PHPT, referred to ASL Città di Torino, Maria Vittoria Hospital, from 2007 to 2019. A PC incidence of 0.05 cases per 100,000 inhabitants was found in our region. Benign forms occurred more frequently in females (

Identifiers

PMID32215010
PMCPMC7079239
OpenAlexW3010553567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.