ArticleJournal of inorganic and organometallic polymers and materials2008
Antiviral and Anticancer Activity of Cisplatin Derivatives of Tilorone.
Article in Journal of inorganic and organometallic polymers and materials, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Functional polymer materials containing heavy group-14 elements focusing on germanium and tin.Smart molecules : open access · 2026Review
- Polymers in the Medical Antiviral Front-Line.Polymers · 2020Review
- Antiviral Activity of Metal-Containing Polymers-Organotin and Cisplatin-Like Polymers.Materials (Basel, Switzerland) · 2011Review
- Structural Consideration in Designing Organotin Polyethers to Arrest the Growth of Breast Cancer Cells In Vitro.Materials (Basel, Switzerland) · 2011Article
- Ability of Group IVB metallocene polyethers containing dienestrol to arrest the growth of selected cancer cell lines.BMC cancer · 2009Article
- Electronic Structure of the d Bent-metallocene Cp(2)VCl(2): A Photoelectron and Density Functional Study.Journal of organometallic chemistry · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cisplatin derivatives containing tilorone and a tilorone derivative were synthesized and characterized employing IR analysis, mass spectrometry, elemental analysis, and chain length. The polymeric cisplatin derivatives prevent growth of four transformed cell lines, L929, 143, Vero, and BS-C-1 and effectively inhibit four viruses including the DNA viruses; herpes simplex-1, vaccinia, and Varicella zoster, and the RNA virus, reovirus in the micrograms/mL range. The tilorone polymers display activity against both transformed cells and DNA and RNA viruses at biologically important concentrations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.