ArticleJournal of inorganic and organometallic polymers and materials2006
Synthesis of Organotin Polyamine Ethers Containing Acyclovir and their Preliminary Anticancer and Antiviral Activity.
Article in Journal of inorganic and organometallic polymers and materials, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 51 citations in OpenAlex.
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- Recent advances in metallopolymer-based drug delivery systems.RSC advances · 2019Review
- Cooperative loading of multisite receptors with lanthanide containers: an approach for organized luminescent metallopolymers.Chemical science · 2018Article
- Metal-containing and related polymers for biomedical applications.Chemical Society reviews · 2016Article
- Raman spectroscopy as a tool to investigate the structure and electronic properties of carbon-atom wires.Beilstein journal of nanotechnology · 2015Review
- Alternative antimicrobial approach: nano-antimicrobial materials.Evidence-based complementary and alternative medicine : eCAM · 2015Review
- Antiviral Activity of Metal-Containing Polymers-Organotin and Cisplatin-Like Polymers.Materials (Basel, Switzerland) · 2011Review
- Structural Consideration in Designing Organotin Polyethers to Arrest the Growth of Breast Cancer Cells In Vitro.Materials (Basel, Switzerland) · 2011Article
- In vitro cytotoxic evaluation of novel dichlorodiorgano[N-(2-pyridylmethylene)arylamine]tin(IV) derivatives in human tumor cell lines.Investigational new drugs · 2010Article
- Triphenyltin(IV) 2-[(E)-2-(aryl)-1-diazenyl]benzoates as anticancer drugs: synthesis, structural characterization, in vitro cytotoxicity and study of its influence towards the mechanistic role of some key enzymes.Investigational new drugs · 2010Article
- Ability of Group IVB metallocene polyethers containing dienestrol to arrest the growth of selected cancer cell lines.BMC cancer · 2009Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organotin polyamine ethers containing acyclovir in their backbone were synthesized in moderate to high yield employing the aqueous interfacial polycondensation system. The products are high molecular weight polymers. Infrared spectroscopy of the products shows new bands characteristic of the formation of Sn-N and Sn-O bonds consistent with the proposed structure. MALDI-TOF MS below 2000 Da shows the presence of organotin and acyclovir units containing these two moieties. The products show moderate inhibition of a number of cancer cell lines and exhibit the ability to inhibit a number of viruses, particularly the herpes simplex virus-1 and varicella zoster virus that are responsible for herpes, chicken pox and shingles.
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