Evidence map›Paper›PMID 32214908›Full record

ArticleMediators of inflammation2020

Monocyte/Lymphocyte Ratio and Cardiovascular Disease Mortality in Peritoneal Dialysis Patients.

Yueqiang Wen, Xiaojiang Zhan, Niansong Wang, FenFen Peng, Xiaoran Feng, Xianfeng Wu

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Yueqiang WenDepartment of Nephrology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xiaojiang ZhanDepartment of Nephrology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Niansong WangDepartment of Nephrology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.ORCID https://orcid.org/0000-0002-5265-5792
FenFen PengDepartment of Nephrology, Zhujiang Hospital of Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0003-2737-1971
Xiaoran FengDepartment of Nephrology, Jiujiang No. 1 People's Hospital, Jiujiang, China.ORCID https://orcid.org/0000-0002-5645-5691
Xianfeng WuDepartment of Nephrology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.ORCID https://orcid.org/0000-0001-7447-5189
Shanghai Jiao Tong University · CNJiujiang First People's Hospital · CNNanchang University · CNSecond Affiliated Hospital of Guangzhou Medical University · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe monocyte-to-lymphocyte ratio (MLR), as a new marker of the systemic inflammatory response, is associated with cardiovascular disease (CVD) mortality in the general population and hemodialysis patients. However, the association between the MLR and CVD mortality in peritoneal dialysis (PD) has received little attention.

methodsIn this multicenter retrospective cohort study, 1753 incident PD patients from November 1, 2005, to June 30, 2017, with a baseline MLR were enrolled. The primary endpoint was CVD mortality. The association of MLR with CVD mortality was assessed using a multivariable-adjusted Cox model and the Fine and Gray competing risk model.

resultsOf 1753 patients, the mean age was 51.1 ± 14.9 years, 56.9% of patients were male, and the Charlson comorbidity index was 4.29 ± 1.75. During the follow-up period of 31.2 ± 18.4 months, 368 patients died, of which 200 (54.3%) deaths were caused by CVD events. CVD mortality rates for the lowest, middle, and highest MLR tertiles were 70.6, 78.4, and 88.9 per 1000 patient-years, respectively (

conclusionsHigher MLR levels at the commencement of PD may be independently associated with increased CVD mortality in PD patients.

Indexed as

AdultAgedCardiovascular DiseasesFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMonocytesMulticenter Studies as TopicPeritoneal DialysisProportional Hazards ModelsRetrospective StudiesRisk Factors

Identifiers

PMID32214908
PMCPMC7048939
OpenAlexW3005855357

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.