ReviewSubstance abuse : research and treatment2020
Prescription Drug Misuse: Taking a Lifespan Perspective.
Review in Substance abuse : research and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Systematic review of the use of prescription and non-prescription psychotropic drugs and their relation with mental health in university population.Frontiers in psychology · 2025Pooled it
- Exploring the Confluence of Animal Medicine and its Implications for Human Health: A Systematic Literature Review.Current neuropharmacology · 2025Pooled it
- Prevalence, Correlates, and Treatment of Major Depression Among Community-Dwelling Adults Aged ≥50 in the US.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026Article
- Late adolescent nonmedical prescription stimulant sources and links to young adult nonmedical stimulant use and sources.Addictive behaviors · 2026Article
- Differences in Substance Use and Mental Health by Sexual Identity Among U.S. Adolescents and Young Adults.LGBT health · 2026Article
- Wastewater Analyses for Psychoactive Substances at Music Festivals: A Systematic Review.Behavioral sciences (Basel, Switzerland) · 2025Review
- US Adolescents' and Young Adults' Sources for Prescription Opioid Misuse: Age, Substance Use, and Mental Health Differences.Pain practice : the official journal of World Institute of Pain · 2025Article
- Prevalence of pharmacotherapy for attention-deficit/hyperactivity disorder and prescription stimulant misuse: A national study of US college students.Addiction (Abingdon, England) · 2025Observational
- Exploring Health Care Professionals' Perspectives on the Use of a Medication and Care Support System and Recommendations for Designing a Similar Tool for Family Caregivers: Interview Study Among Health Care Professionals.JMIR medical informatics · 2024Article
- Factors associated with the use of benzodiazepine and opioid prescription drug in the student population: a cross-sectional study.Scientific reports · 2024Article
- Workplace access, burnout, and prescription drug misuse among Korean hospital nurses: a cross-sectional study.BMC nursing · 2024Article
- Article
- Sources of nonmedically used prescription psychotherapeutic drugs using real-world data from adolescents and adults assessed for substance use treatment--2014-2022.Research in social & administrative pharmacy : RSAP · 2024Article
- Prescription Painkiller Misuse in Hispanic and non-Hispanic Adults Ages 50 and Older: Trends and Correlates in a National Sample, 2015-2019.Substance use & misuse · 2024Article
- User-Guided Enhancements to a Technology-Facilitated Resilience Program to Address Opioid Risks Following Traumatic Injury in Youth: Qualitative Interview Study.JMIR formative research · 2023Article
- Economic Evaluation Design within the HEAL Prevention Cooperative.Prevention science : the official journal of the Society for Prevention Research · 2023Article
- Propofol misuse in medical professions: a scoping review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Article
- Screening the "Invisible Population" of Older Adult Patients for Prescription Pain Reliever Non-Medical Use and Use Disorders.Substance use & misuse · 2023Article
- Predictors of Multiwave Opioid Use Among Older American Adults.Innovation in aging · 2023Article
- Nonpartner Violence Perpetration Among Emerging Adults: Associations With Polysubstance Use and Trait Mindfulness.Psychology of violence · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Prescription drug misuse (PDM), or medication use without a prescription or in ways not intended by the prescriber, is a notable public health concern, especially in the United States. Accumulating research has characterized PDM prevalence and processes, but age-based or lifespan changes in PDM are understudied. Given age-based differences in the medical or developmental concerns that often underlie PDM, it is likely that PDM varies by age. This review summarizes the literature on PDM across the lifespan, examining lifespan changes in prevalence, sources, motives and correlates for opioid, stimulant, and tranquilizer/sedative (or benzodiazepine) PDM. In all, prevalence rates, sources and motives vary considerably by age group, with fewer age-based differences in correlates or risk factors. PDM prevalence rates tend to decline with aging, with greater use of physician sources and greater endorsement of self-treatment motives in older groups. Recreational motives (such as to get high) tend to peak in young adulthood, with greater use of peer sources or purchases to obtain medication for PDM in younger groups. PDM co-occurs with other substance use and psychopathology, including suicidality, across age groups. The evidence for lifespan variation in PDM is strongest for opioid PDM, with a need for more research on tranquilizer/sedative and stimulant PDM. The current literature is limited by the few studies of lifespan changes in PDM within a single sample, a lack of longitudinal research, little research addressing PDM in the context of polysubstance use, and little research on minority groups, such as sexual and gender minorities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.