Evidence map›Paper›PMID 32214728›Full record

ArticleChinese science bulletin = Kexue tongbao2008

Stepwise prediction and statistical screening: B-cell epitopes on neuraminidase of human avian H

Ping Huang, ShouYi Yu, ChangWen Ke

Open access · bronzeAbstract read
In one paragraph

Article in Chinese science bulletin = Kexue tongbao, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Epitope Mapping ofTransboundary and emerging diseases · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Ping Huang1Key Laboratory for Emergency Pathogen Detection, Center for Disease Control and Prevention of Guangdong Province, Guangzhou, 510300 China.
ShouYi Yu2Department of Epidemiology, Southern Medical University, Guangzhou, 510515 China.
ChangWen Ke1Key Laboratory for Emergency Pathogen Detection, Center for Disease Control and Prevention of Guangdong Province, Guangzhou, 510300 China.
Centers for Disease Control and Prevention · USGuangdong Provincial Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The B-cell epitopes of virus are associated with the antiviral drug and the vaccine screening. As the nucleotide sequences of neuraminidase (NA) of stain GD-01-06 were sequenced, we predicted the α-helix and β-fold structure and the indexes of the flexible regions of secondary structure of NA with methods of the Hydrophilicity plot by Kyte-Doolittle, the Surface probability plot by Emini and the Antigenic index by Jameson-Wolf, and then screened statistically the parameters to predict B-cell epitopes by the Hierarchical cluster and the Bivariate correlation and the quartiles with SPSS 13.0. The impact of variation of amino acids in NA on its epitopes was analyzed. The predictive results were evaluated by Wu's Antigenic Index and SWISS-MODEL. We found that the most possible epitopes on NA were located within or nearby its N-terminal Nos. 120-137, 81-84, 408-415, 273-282, 429-432, 356-368, 46-55, 146-155, 341-350 and 198-209, which were the dominant regions of NA epitopes. Peptide 120-137 including the glycoprotein domain (NGT

Indexed as

B-cell epitopeH5N1 virusneuraminidase (NA)predictionscreening

Identifiers

PMID32214728
PMCPMC7088991
OpenAlexW2089336553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.