Evidence map›Paper›PMID 32214541›Full record

ReviewCytology and genetics2009

Role of siRNAs and miRNAs in the processes of RNA-mediated gene silencing during viral infections.

I Krulko, D Ustyanenko, V Polischuk

Abstract readReview
In one paragraph

Review in Cytology and genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

I KrulkoTaras Shevchenko Kyiv National University, ul. Volodymyrska 64, Kyiv, 01033 Ukraine.
D UstyanenkoTaras Shevchenko Kyiv National University, ul. Volodymyrska 64, Kyiv, 01033 Ukraine.
V PolischukTaras Shevchenko Kyiv National University, ul. Volodymyrska 64, Kyiv, 01033 Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenomenon of RNA-induced gene silencing is a highly conservative mechanism among eukaryotic organisms. Several classes of small RNAs (siRNAs and miRNAs) 21-25 nt in length, which play a significant role in the processes of development of an organism, occurred important components of antiviral defence in animals and plants. This review shortly describes the main stages of gene silencing mechanism, features of antiviral RNA silencing in plants, invertebrates, mammals, ways of suppression of RNA-interference by viruses, as well as possible approaches of utilization of abovementioned phenomenon for struggling against viral infections.

Indexed as

antiviralgene silencinginterferencemiRNAssiRNAstransformation

Identifiers

PMID32214541
PMCPMC7089099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.