Evidence map›Paper›PMID 32214420›Full record

ArticleChemistry of heterocyclic compounds2017

Privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro[5.5]undecane-containing compounds.

Daniel Blanco-Ania, Rik Heus, Floris P J T Rutjes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry of heterocyclic compounds, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel Blanco-AniaRadboud University, Institute for Molecules and Materials, Heyendaalseweg 135, 6526 AJ Nijmegen, the Netherlands.
Rik HeusRadboud University, Institute for Molecules and Materials, Heyendaalseweg 135, 6526 AJ Nijmegen, the Netherlands.
Floris P J T RutjesRadboud University, Institute for Molecules and Materials, Heyendaalseweg 135, 6526 AJ Nijmegen, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review discusses the biological activity and synthesis of 1,9-diazaspiro[5.5]undecanes, including those ring-fused with arenes and heteroarenes and/or containing a carbonyl group at position 2. These compounds could be used for the treatment of obesity, pain, as well as various immune system, cell signaling, cardiovascular, and psychotic disorders.

Indexed as

1,9-diazaspiro[5.5]undecan-2-one1,9-diazaspiro[5.5]undecaneobesitypain treatmentspiro dipiperidines

Identifiers

PMID32214420
PMCPMC7088121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.