Evidence map›Paper›PMID 32214412›Full record

ArticleBiologia2012

Expression of recombinant herpes simplex virus type 2 glycoprotein D by high-density cell culture of

Tao Liu, Ji-Feng Liu, Hui-Jun Dong, Wei Zheng, Zhi-Cheng Huang, Shui-Fen Zhu

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biologia, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tao Liu1Microbiology Laboratory, Hangzhou Center for Disease Control and Prevention, Hangzhou, 310021 People's Republic of China.
Ji-Feng LiuDepartment of Dermatology, The Third Hospital of Hangzhou, Hangzhou, 310009 People's Republic of China.
Hui-Jun DongLunan Pharmaceutical Group Corporation, Linyi, 273400 People's Republic of China.
Wei Zheng1Microbiology Laboratory, Hangzhou Center for Disease Control and Prevention, Hangzhou, 310021 People's Republic of China.
Zhi-Cheng Huang1Microbiology Laboratory, Hangzhou Center for Disease Control and Prevention, Hangzhou, 310021 People's Republic of China.
Shui-Fen Zhu1Microbiology Laboratory, Hangzhou Center for Disease Control and Prevention, Hangzhou, 310021 People's Republic of China.
Hangzhou Center for Disease Control and Prevention · CNThird People's Hospital of Hangzhou · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus type 2 (HSV-2) is the major cause of genital herpes in humans. The glycoprotein D of HSV-2 (gD2) is a promising subunit vaccine candidate for the treatment of genital herpes. The aim of the present study was to express a biologically active recombinant gD2 in eukaryotic baculovirus system in quantities sufficient for further studies. Human cDNA encoding a gD2 protein with 393 amino acids was subcloned into the pFastBac HTb vector and the recombinant protein was expressed in

Indexed as

glycoprotein Dguinea pigherpes simplex virus type 2high-density cell cultureSf9 cells

Identifiers

PMID32214412
PMCPMC7088583
OpenAlexW2027117938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.