Evidence map›Paper›PMID 32214394›Full record

ArticlePLoS pathogens2020

Maternal gatekeepers: How maternal antibody Fc characteristics influence passive transfer and infant protection.

Stephanie N Langel, Claire E Otero, David R Martinez, Sallie R Permar

Abstract read
In one paragraph

Article in PLoS pathogens, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. B Cell Responses to the Placenta and Fetus.Annual review of pathology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephanie N LangelDuke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.ORCID 0000-0002-0467-7874
Claire E OteroDuke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.ORCID 0000-0001-7127-2327
David R MartinezDepartment of Epidemiology, University of North Carolina at Chapel Hill School of Public Health, Chapel Hill, North Carolina, United States of America.
Sallie R PermarDuke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.ORCID 0000-0003-1438-4554

Funding

Virology CoreP01AI129859 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI Sallie R. Permar · 2019 to 2026
$31.0M
Project 2: RNA vaccination in early life to induce potent and broad HIV Env-specific antibody responsesP01AI117915 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI DE PARIS, KRISTINA, PERMAR, SALLIE R. · 2015 to 2024
$21.2M
Ruth L. Kirschstein National Research Service Award (NRSA)- T32T32AI007392 · NIAID · DUKE UNIVERSITY · PI Amy Lynn Corneli, Guido Ferrari · 1990 to 2026
$9.8M
Viral Oncology Training GrantT32CA009111 · NCI · DUKE UNIVERSITY · PI LUFTIG, MICAH A. · 1985 to 2023
$8.9M
INFECTIOUS DISEASE PATHOGENESIS TRAININGT32AI007151 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JULIANO, JONATHAN J · 1985 to 2024
$5.5M
Role of neutralizing antibodies in HIV-1-infected and vaccinated mothers in MTCTR01AI122909 · NIAID · DUKE UNIVERSITY · PI KUMAR, AMIT · 2016 to 2019
$2.6M
NCI NIH HHS T32 CA009111NIAID NIH HHS P01 AI117915NIAID NIH HHS P01 AI129859NIAID NIH HHS R01 AI122909NIAID NIH HHS T32 AI007151NIAID NIH HHS T32 AI007392
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immunity, Maternally-AcquiredFemaleHumansImmunization, PassiveImmunoglobulin Fc FragmentsInfantMaleReceptors, FcImmunoglobulin Fc FragmentsReceptors, Fc

Identifiers

PMID32214394
PMCPMC7098569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.