Evidence map›Paper›PMID 32214343›Full record

ArticlePloS one2020

Objective evaluation of visual fatigue in patients with intermittent exotropia.

Masakazu Hirota, Kozue Yada, Takeshi Morimoto, Takao Endo, Tomomitsu Miyoshi, Suguru Miyagawa, Yoko Hirohara, Tatsuo Yamaguchi, Makoto Saika, Takashi Fujikado

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Masakazu HirotaDepartment of Applied Visual Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.ORCID 0000-0003-1420-9844
Kozue YadaDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Takeshi MorimotoDepartment of Applied Visual Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Takao EndoDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Tomomitsu MiyoshiDepartment of Integrative Physiology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Suguru MiyagawaDepartment of Applied Visual Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Yoko HiroharaDepartment of Applied Visual Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Tatsuo YamaguchiTopcon Corporation, Tokyo, Japan.
Makoto SaikaTopcon Corporation, Tokyo, Japan.
Takashi FujikadoDepartment of Applied Visual Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
The University of Osaka · JPTopcon (Japan) · JPTeikyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to evaluate the degree of visual fatigue in patients with intermittent exotropia (IXT) using the binocular fusion maintenance (BFM) test.

methodsFourteen patients with IXT (32.1 ± 16.4 years) and 15 age-matched healthy volunteers (31.2 ± 9.3 years) participated in the study. BFM was assessed by measuring the transmittance of liquid crystals placed in front of the subject's nondominant eye at the instance when binocular fusion was broken and vergence eye movement was induced. A questionnaire on subjective symptoms was administered to the subjects before and after the visual task. The visual task consisted of a reciprocal movement between 67 and 40 cm.

resultsThe change [post-pre] of BFM was significantly lower in the IXT group (-0.185 ± 0.187) than in the control group (-0.030 ± 0.070) (P = 0.010). The change of total subjective eye symptom score was significantly greater in the IXT group (2.28 ± 1.43) than in the control group (0.93 ± 1.27) (P = 0.018). The reduction in BFM rate with increasing total subjective eye symptom score was significantly greater in the IXT group (-0.106 ± 0.017) than in the control group (-0.030 ± 0.013) (P = 0.006).

conclusionThe present findings objectively showed that patients with IXT are at a greater risk of visual fatigue in comparison with healthy individuals.

Indexed as

Vision, OcularAdolescentAdultCase-Control StudiesExotropiaFemaleHumansMaleMiddle AgedYoung Adult

Identifiers

PMID32214343
PMCPMC7098610
OpenAlexW3013022058

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.