Evidence map›Paper›PMID 32214281›Full record

ArticleEuropean journal of histochemistry : EJH2020

Immuno- and glyco-histochemistry as a tool to evaluate the oregano supplemented feed effects in pig gut.

Cecilia Dall'Aglio, Francesca Mercati, Valerio Faeti, Gabriele Acuti, Massimo Trabalza Marinucci, Elena De Felice, Federico Maria Tardella, Maria Pia Franciosini, Patrizia Casagrande Proietti, Daniele Catorci and 3 more

Open access · goldAbstract read
In one paragraph

Article in European journal of histochemistry : EJH, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. A Detailed Study of Rainbow Trout (Animals : an open access journal from MDPI · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Cecilia Dall'AglioDepartment of Veterinary Medicine, University of Perugia. cecilia.dallaglio@unipg.it.
Francesca Mercati
Valerio Faeti
Gabriele Acuti
Massimo Trabalza Marinucci
Elena De Felice
Federico Maria Tardella
Maria Pia Franciosini
Patrizia Casagrande Proietti
Daniele Catorci
Paolo Stacchini
Augusto Pastorelli
Paola Scocco
University of Perugia · ITUniversità di Camerino · ITIstituto Superiore di Sanità · ITUniversity of Trento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among oregano properties, its antioxidant and antibacterial effects are particularly interesting. Oregano is also able to induce a higher glycoconjugate production in gut, creating a physical barrier against microorganisms. This study evaluated the effects of adding an aqueous extract of oregano (OAE) to the diet of two homogenous groups of pigs during the finisher phase. The diets were as follows: control commercial diet (CTR group) and CTR diet supplemented (2 g/kg) with OAE (O group). Samples of ileum and caecum from the two groups were examined by conventional histochemistry to analyze complex carbohydrates and by immunohistochemistry to detect Bcl-2 Associate X protein (BAX), an indicator of oxidative stress. Glyco-histochemistry showed significant differences between the two groups. Immunohistochemistry revealed a lower presence of BAX in O group. The OAE supplementation improved the production of glycoconjugates, able to enhance in pig the protection of intestinal mucosa by means of direct and indirect defense actions. The reduced BAX immunostaining observed in O group may be an indicator of enhanced antioxidant action promoted by oregano. The results of this study can be used in further research to identify ways to improve endogenous defence ability, with the aim of reducing antibiotic use and preventing antimicrobial resistance.

Indexed as

Dietary SupplementsAnimalsAntibodies, Monoclonalbcl-2-Associated X ProteinCecumGlycoconjugatesIleumImmunohistochemistryMiceOriganumPlant ExtractsSwineAntibodies, Monoclonalbcl-2-Associated X ProteinGlycoconjugatesPlant Extracts

Identifiers

PMID32214281
PMCPMC7058963
OpenAlexW3007150145

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.