Evidence map›Paper›PMID 32214244›Full record

ArticleNature2020

Microbiome analyses of blood and tissues suggest cancer diagnostic approach.

Gregory D Poore, Evguenia Kopylova, Qiyun Zhu, Carolina Carpenter, Serena Fraraccio, Stephen Wandro, Tomasz Kosciolek, Stefan Janssen, Jessica Metcalf, Se Jin Song and 7 more

RetractedOpen access · greenAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 629 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
629citing papers in PubMed, 1 pooled it
56.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

629 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,023 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Article
  4. Article
  5. The multi-omics fallacy in microbiome science.PLoS computational biology · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. A tumor-residentiScience · 2026
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

569 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 3 countries.

Gregory D Poore *Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.
Evguenia Kopylova *Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Qiyun ZhuDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-3568-6271
Carolina CarpenterCenter for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA.
Serena FraraccioCenter for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA.
Stephen WandroCenter for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA.
Tomasz KosciolekDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-9915-7387
Stefan JanssenDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-0955-0589
Jessica MetcalfDepartment of Animal Sciences, Colorado State University, Fort Collins, CO, USA.
Se Jin SongCenter for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-0750-5709
Jad KanbarDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Sandrine Miller-MontgomeryDepartment of Bioengineering, University of California San Diego, La Jolla, CA, USA.
Robert HeatonDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Rana MckayMoores Cancer Center, University of California San Diego Health, La Jolla, CA, USA.
Sandip Pravin PatelCenter for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA.
Austin D SwaffordCenter for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA.
Rob KnightDepartment of Bioengineering, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.ORCID http://orcid.org/0000-0002-0975-9019
University of California San Diego · USColorado State University · USJagiellonian University · PLJustus-Liebig-Universität Gießen · DE

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jesse Nodora · 1985 to 2026
$124.9M
STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello · 2001 to 2026
$50.4M
Translational Methamphetamine AIDS Research Center (TMARC)P50DA026306 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GRANT, IGOR · 2009 to 2018
$33.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007198 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHI, NEIL C, INSEL, PAUL A · 1985 to 2024
$29.3M
NEUROMOTORP01DA012065 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LETENDRE, SCOTT L · 1999 to 2009
$17.8M
COMT Genotype and Risky Decision Making in HIV and Methamphetamine DependenceR01DA026334 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHERNER, MARIANA · 2009 to 2010
$1.1M
Impact of Alcohol Use and HIV Infection on Brain Connectivity AbnormalitiesR00AA020235 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GONGVATANA, ASSAWIN · 2013 to 2015
$732k
Comprehensive characterization of the cancer microbiome and its immuno-oncology interfaceF30CA243480 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI POORE, GREGORY DERRICK · 2020 to 2021
$73k
NCI NIH HHS F30 CA243480NCI NIH HHS HHSN261201400008CNCI NIH HHS HHSN261201500003CNCI NIH HHS HHSN261201500003INCI NIH HHS P30 CA023100NIAAA NIH HHS R00 AA020235NIDA NIH HHS P01 DA012065NIDA NIH HHS P50 DA026306NIDA NIH HHS R01 DA026334NIGMS NIH HHS T32 GM007198NIMH NIH HHS P30 MH062512
6 · The paper itself

Abstract

Systematic characterization of the cancer microbiome provides the opportunity to develop techniques that exploit non-human, microorganism-derived molecules in the diagnosis of a major human disease. Following recent demonstrations that some types of cancer show substantial microbial contributions

Indexed as

Case-Control StudiesCohort StudiesDatasets as TopicDNA, BacterialDNA, ViralFemaleHumansLiquid BiopsyLung NeoplasmsMaleMelanomaMicrobiotaNeoplasmsPlasmaProstatic NeoplasmsReproducibility of ResultsDNA, BacterialDNA, Viral

Identifiers

PMID32214244
PMCPMC7500457
OpenAlexW3010810358

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.