Evidence map›Paper›PMID 32214194›Full record

ArticleScientific reports2020

Application of random forest based approaches to surface-enhanced Raman scattering data.

Stephan Seifert

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
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  8. Article
  9. Raman spectroscopy for agricultural applications.Frontiers in plant science · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Machine learning analysis of SERS fingerprinting for the rapid determination ofComputational and structural biotechnology journal · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Stephan SeifertKiel University, University Hospital Schleswig-Holstein, Institute of Medical Informatics and Statistics, Kiel, 24105, Germany. Stephan.Seifert@chemie.uni-hamburg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surface-enhanced Raman scattering (SERS) is a valuable analytical technique for the analysis of biological samples. However, due to the nature of SERS it is often challenging to exploit the generated data to obtain the desired information when no reporter or label molecules are used. Here, the suitability of random forest based approaches is evaluated using SERS data generated by a simulation framework that is also presented. More specifically, it is demonstrated that important SERS signals can be identified, the relevance of predefined spectral groups can be evaluated, and the relations of different SERS signals can be analyzed. It is shown that for the selection of important SERS signals Boruta and surrogate minimal depth (SMD) and for the analysis of spectral groups the competing method Learner of Functional Enrichment (LeFE) should be applied. In general, this investigation demonstrates that the combination of random forest approaches and SERS data is very promising for sophisticated analysis of complex biological samples.

Identifiers

PMID32214194
PMCPMC7096517

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.