Evidence map›Paper›PMID 32214132›Full record

ArticleScientific reports2020

Sustained virological response to hepatitis C therapy does not decrease the incidence of systemic lupus erythematosus or rheumatoid arthritis.

Wei-Fan Hsu, Chi-Yi Chen, Kuo-Chih Tseng, Hsueh-Chou Lai, Hsing-Tao Kuo, Chao-Hung Hung, Shui-Yi Tung, Jing-Houng Wang, Jyh-Jou Chen, Pei-Lun Lee and 28 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 16 institutions in 1 country.

Wei-Fan HsuCenter for Digestive Disease, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.ORCID http://orcid.org/0000-0002-0738-417X
Chi-Yi ChenDepartment of Internal Medicine, Chiayi Christian Hospital, Chiayi, Taiwan.
Kuo-Chih TsengDepartment of Gastroenterology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
Hsueh-Chou LaiCenter for Digestive Disease, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
Hsing-Tao KuoDivision of Hepato-gastroenterology, Department of Internal Medicine, Chi-Mei Medical Center, Tainan, Taiwan.
Chao-Hung HungDivision of Hepatogastroenterology, Department of Internal Medicine, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan.
Shui-Yi TungDivision of Hepatogastroenterology, Department of Internal Medicine, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan.
Jing-Houng WangDivision of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Jyh-Jou ChenDivision of Gastroenterology and Hepatology, Chi-Mei Medical Center, Liouying, Tainan, Taiwan.
Pei-Lun LeeDivision of Gastroenterology and Hepatology, Chi-Mei Medical Center, Liouying, Tainan, Taiwan.
Rong-Nan ChienDivision of Hepatology, Department of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Chun-Yen LinDivision of Hepatology, Department of Gastroenterology and Hepatology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.ORCID http://orcid.org/0000-0003-3007-3190
Chi-Chieh YangDivision of Gastroenterology, Department of Internal Medicine, Show-Chwan Memorial Hospital, Changhua, Taiwan.
Gin-Ho LoDivision of Gastroenterology and Hepatology, Department of Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.
Chi-Ming TaiDivision of Gastroenterology and Hepatology, Department of Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.
Chih-Wen LinDivision of Gastroenterology and Hepatology, Department of Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.
Jia-Horng KaoGraduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID http://orcid.org/0000-0002-2442-7952
Chun-Jen LiuGraduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID http://orcid.org/0000-0001-8082-7144
Chen-Hua LiuGraduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.ORCID http://orcid.org/0000-0003-3622-9707
Sheng-Lei YanDivision of Gastroenterology, Department of Internal Medicine, Chang Bing Show-Chwan Memorial Hospital, Changhua, Taiwan.
Ming-Jong BairDivision of Gastroenterology, Department of Internal Medicine, Taitung Mackay Memorial Hospital, Taitung, Taiwan.
Wei-Wen SuDivision of Gastroenterology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.
Cheng-Hsin ChuDivision of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
Chih-Jen ChenDivision of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
Ching-Chu LoDepartment of Internal Medicine, St. Martin De Porres Hospital - Daya, Chiayi, Taiwan.
Pin-Nan ChengDivision of Gastroenterology and Hepatology, Department of Internal Medicine, National Cheng Kung University Hospital; College of Medicine, National Cheng Kung University, Tainan, Taiwan.ORCID http://orcid.org/0000-0001-9331-9018
Yen-Cheng ChiuDivision of Gastroenterology and Hepatology, Department of Internal Medicine, National Cheng Kung University Hospital; College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chia-Chi WangDivision of Gastroenterology, Department of Internal Medicine, Taipei Tzuchi Hospital, New Taipei City, Taiwan.
Jin-Shiung ChengDivision of Gastroenterology and Hepatology, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Wei-Lun TsaiDivision of Gastroenterology and Hepatology, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Han-Chieh LinDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Yi-Hsiang HuangDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.ORCID http://orcid.org/0000-0001-5241-5425
Pei-Chien TsaiHepatobiliary Division, Department of Internal Medicine and Hepatitis Center Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Jee-Fu HuangHepatobiliary Division, Department of Internal Medicine and Hepatitis Center Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chia-Yen DaiHepatobiliary Division, Department of Internal Medicine and Hepatitis Center Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Wan-Long ChuangHepatobiliary Division, Department of Internal Medicine and Hepatitis Center Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Ming-Lung YuHepatobiliary Division, Department of Internal Medicine and Hepatitis Center Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. fish6069@gmail.com.ORCID http://orcid.org/0000-0001-8145-1900
Cheng-Yuan PengCenter for Digestive Disease, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan. cypeng@mail.cmuh.org.tw.ORCID http://orcid.org/0000-0001-9030-6086
Kaohsiung Medical University · TWE-Da Hospital · TWMackay Memorial Hospital · TWChi Mei Medical Center · TWChina Medical University · TWNational Taiwan University · TWChang Bing Show Chwan Memorial Hospital · TWChiayi Chang Gung Memorial Hospital · TWKaohsiung Veterans General Hospital · TWNational Cheng Kung University Hospital · TWTaipei Veterans General Hospital · TWChang Gung University · TWChanghua Christian Hospital · TWLinkou Chang Gung Memorial Hospital · TWSt. Martin de Porres Hospital · TWTaipei Tzu Chi Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with chronic hepatitis C (CHC), the effects of baseline characteristics, virological profiles, and therapeutic outcome to pegylated interferon plus ribavirin (PR) therapy on autoimmune diseases are unknown. Taiwanese Chronic Hepatitis C Cohort is a nationwide hepatitis C virus registry cohort comprising 23 hospitals of Taiwan. A total of 12,770 CHC patients receiving PR therapy for at least 4 weeks between January 2003 and December 2015 were enrolled and their data were linked to the Taiwan National Health Insurance Research Database for studying the development of 10 autoimmune diseases. The mean follow-up duration was 5.3 ± 2.9 years with a total of 67,930 person-years, and the annual incidence of systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA) was 0.03%. Other autoimmune diseases were not assessable due to few events. Body mass index ≥24 kg/m

Indexed as

AdultAntiviral AgentsArthritis, RheumatoidAutoimmune DiseasesCohort StudiesDrug Therapy, CombinationFemaleHepatitis CHepatitis C, ChronicHumansIncidenceInterferon-alphaLupus Erythematosus, SystemicMaleMiddle AgedPolyethylene GlycolsAntiviral AgentsInterferon-alphaPolyethylene GlycolsRibavirin

Identifiers

PMID32214132
PMCPMC7096452
OpenAlexW3013889062

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.