Evidence map›Paper›PMID 32214021›Full record

ArticleNutrients2020

Cytoprotective Effects of Natural Highly Bio-Available Vegetable Derivatives on Human-Derived Retinal Cells.

Ingrid Munia, Laurent Gafray, Marie-Agnès Bringer, Pablo Goldschmidt, Lil Proukhnitzky, Nathalie Jacquemot, Christine Cercy, Khaoula Ramchani Ben Otman, Marie Hélène Errera, Isabelle Ranchon-Cole

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  8. Article
  9. Review
  10. New Insights into Dose-Dependent Effects of Curcumin on ARPE-19 Cells.International journal of molecular sciences · 2022
    Article
  11. Review
  12. Review
  13. Recent Advances and Disputes About Curcumin in Retinal Diseases.Clinical ophthalmology (Auckland, N.Z.) · 2021
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ingrid MuniaUMR1107 NeuroDol, Université Clermont-Auvergne, TSA 50400, 28 Place Henri Dunant, 63000 Clermont-Ferrand, France.
Laurent GafrayUMR1107 NeuroDol, Université Clermont-Auvergne, TSA 50400, 28 Place Henri Dunant, 63000 Clermont-Ferrand, France.
Marie-Agnès BringerCentre des Sciences du Goût et de l'Alimentation, AgroSup Dijon, CNRS, INRAE, University of Bourgogne Franche-Comté, Eye and Nutrition Research Group, F-21000 Dijon, France.
Pablo GoldschmidtCentre Hospitalier National d'Ophtalmologie des Quinze-Vingts, 75012 Paris, France.
Lil ProukhnitzkyCentre des Sciences du Goût et de l'Alimentation, AgroSup Dijon, CNRS, INRAE, University of Bourgogne Franche-Comté, Eye and Nutrition Research Group, F-21000 Dijon, France.
Nathalie JacquemotUMR1107 NeuroDol, Université Clermont-Auvergne, TSA 50400, 28 Place Henri Dunant, 63000 Clermont-Ferrand, France.
Christine CercyUMR1107 NeuroDol, Université Clermont-Auvergne, TSA 50400, 28 Place Henri Dunant, 63000 Clermont-Ferrand, France.
Khaoula Ramchani Ben OtmanUMR1107 NeuroDol, Université Clermont-Auvergne, TSA 50400, 28 Place Henri Dunant, 63000 Clermont-Ferrand, France.
Marie Hélène ErreraCentre Hospitalier National d'Ophtalmologie des Quinze-Vingts, 75012 Paris, France.
Isabelle Ranchon-ColeUMR1107 NeuroDol, Université Clermont-Auvergne, TSA 50400, 28 Place Henri Dunant, 63000 Clermont-Ferrand, France.ORCID 0000-0002-7092-6744
Université Clermont Auvergne · FRCentre hospitalier national d'ophtalmologie des Quinze-Vingts · FRCentre National de la Recherche Scientifique · FR

Funding

Densmore Monaco R17PRATDensmore Monaco R18RPRCC
6 · The paper itself

Abstract

Retinal pigment epithelial cells are crucial for retina maintenance, making their cytoprotection an excellent way to prevent or slow down retinal degeneration. In addition, oxidative stress, inflammation, apoptosis, neovascularization, and/or autophagy are key pathways involved in degenerative mechanisms. Therefore, here we studied the effects of curcumin, lutein, and/or resveratrol on human retinal pigment epithelial cells (ARPE-19). Cells were incubated with individual or combined agent(s) before induction of (a) H

Indexed as

ApoptosisAutophagyBiological ProductsCells, CulturedCell SurvivalCytoprotectionDose-Response Relationship, DrugEpithelial CellsHumansOxidative StressPlant ExtractsProtective AgentsReactive Oxygen SpeciesRetinaRetinal Pigment EpitheliumVegetablesBiological ProductsPlant ExtractsProtective AgentsReactive Oxygen Speciesantioxidantapoptosisautophagydamageluteinprotection curcuminresveratrolretina

Identifiers

PMID32214021
PMCPMC7146218
OpenAlexW3013884816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.