Evidence map›Paper›PMID 32213958›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Virulence-Inhibiting Herbal Compound Falcarindiol Significantly Reduced Mortality in Mice Infected with

Pansong Zhang, Qiaolian Wu, Lin Chen, Kangmin Duan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Anti-QS Strategies AgainstMicroorganisms · 2025
    Review
  2. Article
  3. Scopoletin and Scoparone fromInfection and drug resistance · 2025
    Article
  4. Falcarindiol Isolated fromMolecules (Basel, Switzerland) · 2021
    Article
  5. Review
  6. Baicalin Represses Type Three Secretion System ofMolecules (Basel, Switzerland) · 2021
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Pansong ZhangKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China.
Qiaolian WuKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China.
Lin ChenKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, Shaanxi 710069, China.
Kangmin DuanDepartment of Oral Biology & Medical Microbiology & Infectious Diseases, Rady Faculty of Health Sciences, University of Manitoba, 780 Bannatyne Ave., Winnipeg, MB R3E 0W2, Canada.
Ministry of Education of the People's Republic of China · CNUniversity of Manitoba · CA

Funding

National Science and Engineering Research Council of Canada 402943-2011 RGPINNatural Science Foundation of Shaanxi Province 2018JM3013Natural Science Foundation of Shaanxi Provincial Department of Education 16JK1783Opening Foundation of Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education ZSK2018007the MOE of China No. IRT_15R55
6 · The paper itself

Abstract

Antipathogenic compounds that target the virulence of pathogenic bacteria rather than their viability offer a promising alternative approach to treat infectious diseases. Using extracts from 30 Chinese herbs that are known for treating symptoms resembling infections, we identified an active compound falcarindiol from

Indexed as

antibioticsanti-virulence therapeuticfalcarindiolPseudomonas aeruginosaquorum sensingtype III secretion system

Identifiers

PMID32213958
PMCPMC7148489
OpenAlexW3013385399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.