ArticlemSphere2020
Natural Transmission of Helicobacter saguini Causes Multigenerational Inflammatory Bowel Disease in C57/129 IL-10
Anthony Mannion, Zeli Shen, Yan Feng, Dylan Puglisi, Sureshkumar Muthupalani, Mark T Whary, James G Fox
Open access · goldAbstract read
In one paragraphArticle in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 3 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors at 1 institution in 1 country.
Anthony MannionDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA manniona@mit.edu jgfox@mit.edu.
Zeli ShenDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Yan FengDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Dylan PuglisiDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Sureshkumar MuthupalaniDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Mark T WharyDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
James G FoxDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA manniona@mit.edu jgfox@mit.edu.
Massachusetts Institute of Technology · US
Funding
TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI YAFFE, MICHAEL B · 1985 to 2020
$25.6MThe Role of Stem Cells and the Microenvironment in Gastrointestinal CancersR35CA210088 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Timothy Cragin Wang · 2017 to 2026
$10.2MBiomedical Research Training for Veterinary ScientistsT32OD010978 · OD · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI FOX, JAMES G · 2012 to 2017
$2.2MNCI NIH HHS R35 CA210088NIEHS NIH HHS P30 ES002109NIH HHS T32 OD010978
6 · The paper itselfAbstract
Cotton-top tamarins (CTTs) are an ideal model of human inflammatory bowel disease (IBD) because these animals develop multigenerational, lower bowel cancer. We previously isolated and characterized a novel enterohepatic
Indexed as
Infectious Disease Transmission, VerticalAnimalsCytokinesDisease Models, AnimalFemaleGenome, BacterialHelicobacterHelicobacter InfectionsInflammatory Bowel DiseasesInterleukin-10MaleMiceMice, Inbred C57BLMice, KnockoutSpecific Pathogen-Free OrganismsVirulence FactorsCytokinesIL10 protein, mouseInterleukin-10Virulence Factorscotton-top tamarinsDNA damagegermfree IL-10−/− miceHelicobacterinflammatory bowel diseasemicrobiomemicroevolutionsmultigenerationalwhole-genome sequencing
Identifiers
PMID32213619
PMCPMC7096620
OpenAlexW3013478461
What OpenQuestion holds
Textmetadata
LicenceCC BY
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