Evidence map›Paper›PMID 32213532›Full record

ArticleG3 (Bethesda, Md.)2020

Tunable Transcriptional Interference at the Endogenous Alcohol Dehydrogenase Gene Locus in

Victoria Jorgensen, Jingxun Chen, Helen Vander Wende, Devon E Harris, Alicia McCarthy, Shane Breznak, Siu Wah Wong-Deyrup, Yuzhang Chen, Prashanth Rangan, Gloria Ann Brar and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Victoria JorgensenDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA 94720.ORCID 0000-0002-4205-6198
Jingxun ChenDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA 94720.ORCID 0000-0001-7320-8652
Helen Vander WendeDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA 94720.ORCID 0000-0002-0292-4528
Devon E HarrisDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA 94720.ORCID 0000-0001-6406-1054
Alicia McCarthyDepartment of Biological Sciences/ The RNA Institute, University at Albany SUNY, NY 12222.
Shane BreznakDepartment of Biological Sciences/ The RNA Institute, University at Albany SUNY, NY 12222.
Siu Wah Wong-DeyrupDepartment of Biological Sciences/ The RNA Institute, University at Albany SUNY, NY 12222.
Yuzhang ChenDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA 94720.ORCID 0000-0002-7377-861X
Prashanth RanganDepartment of Biological Sciences/ The RNA Institute, University at Albany SUNY, NY 12222.ORCID 0000-0002-1452-8119
Gloria Ann BrarDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA 94720.
Eric M SawyerDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA 94720 elcin@berkeley.edu.ORCID 0000-0003-1160-3838
Leon Y ChanDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA 94720 elcin@berkeley.edu.ORCID 0000-0002-0189-4689
Elçin ÜnalDepartment of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, CA 94720 elcin@berkeley.edu.ORCID 0000-0002-6768-609X
University of California, Berkeley · USUniversity at Albany, State University of New York · US

Funding

Dissecting the roles of pervasive short ORFs in meiosisDP2GM119138 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BRAR, GLORIA ANN · 2015 to 2015
$2.4M
ILLUMINATING CELLULAR AGING PATHWAYS THROUGH GAMETOGENESISDP2AG055946 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI UNAL, ELCIN · 2016 to 2016
$2.2M
LTQ XL Linear Quadrupole Ion Trap Mass SpectrometerS10RR025622 · NCRR · UNIVERSITY OF CALIFORNIA BERKELEY · PI KOHLSTAEDT, LORI · 2009 to 2009
$463k
NCRR NIH HHS S10 RR025622NIA NIH HHS DP2 AG055946NIGMS NIH HHS DP2 GM119138
6 · The paper itself

Abstract

Neighboring sequences of a gene can influence its expression. In the phenomenon known as transcriptional interference, transcription at one region in the genome can repress transcription at a nearby region in

Indexed as

Alcohol DehydrogenaseDrosophila melanogasterAnimalsDrosophilaPromoter Regions, GeneticTranscription, GeneticAlcohol DehydrogenaseAdhCas9chromatinCRISPRDrosophilaH3K36me3interferencetranscriptiontranslation

Identifiers

PMID32213532
PMCPMC7202008
OpenAlexW3013863362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.