Evidence map›Paper›PMID 32213111›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2020

A chronic high-fat diet exacerbates contractile dysfunction with impaired intracellular Ca

Hiroaki Eshima, Yoshifumi Tamura, Saori Kakehi, Ryo Kakigi, Ryota Hashimoto, Katsuhiko Funai, Ryuzo Kawamori, Hirotaka Watada

Open access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

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  19. Low lysophosphatidylcholine induces skeletal muscle myopathy that is aggravated by high-fat diet feeding.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Hiroaki EshimaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yoshifumi TamuraDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Saori KakehiDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Ryo KakigiDepartment of Physiology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Ryota HashimotoDepartment of Physiology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Katsuhiko FunaiDiabetes & Metabolism Research Center, University of Utah, Salt Lake City, Utah.
Ryuzo KawamoriDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hirotaka WatadaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Juntendo University · JPUniversity of Utah · US

Funding

WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
PE methylation in skeletal muscle energy efficiencyR01DK107397 · NIDDK · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI FUNAI, KATSUHIKO · 2017 to 2025
$3.8M
Mitochondrial phospholipids, ROS, and disuse atrophyR21AG063077 · NIA · UNIVERSITY OF UTAH · PI FUNAI, KATSUHIKO · 2019 to 2020
$419k
NIA NIH HHS R21 AG063077NIDDK NIH HHS P30 DK020579NIDDK NIH HHS R01 DK107397
6 · The paper itself

Abstract

Obesity and aging reduce skeletal muscle contractile function. However, it remains unclear whether obesity additively promotes muscle contractile dysfunction in the setting of aging. In this study, we investigated skeletal muscle contractile function ex vivo and intracellular Ca

Indexed as

Diet, High-FatMuscle ContractionAnimalsMaleMiceMice, Inbred C57BLMuscle, SkeletalObesityagingcalciumhigh-fat dietmuscle contractionobesity

Identifiers

PMID32213111
PMCPMC7276930
OpenAlexW3013389432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.