SynthesisUnited European gastroenterology journal2020
Endoscopic papillectomy for neoplastic ampullary lesions: A systematic review with pooled analysis.
Synthesis in United European gastroenterology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05690412 (Efficacy and Safety of Endoscopic Papillectomy in the Treatment of Ampullary Neoplasms), which is not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy and Safety of Endoscopic Papillectomy in the Treatment of Ampullary Neoplasms: a Multicenter, Retrospective, Nationwide Study.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Therapeutic strategies and outcomes in the management of ampullary tumours: meta-analysis.BJS open · 2026Pooled it
- Guideline
- Guideline
- Evaluation of Additional Treatment for Residual Cases After Endoscopic Papillectomy of Duodenal Ampullary Tumors.DEN open · 2027Article
- Endoscopic Papillectomy for Ampullary Tumors in Older Patients: Balancing Oncologic Benefit and Geriatric Risk.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
- Ducts-first stenting strategy for zonal hybrid resection of an ampullary neuroendocrine tumor.Endoscopy · 2026Article
- A Novel Closure Technique after Endoscopic Papillectomy Using the Endoscopic Purse-String Suture Device.Endoscopy · 2026Article
- Nationwide Survey on Endoscopic Papillectomy for Ampullary Adenoma: Current Practices and Variability.Gut and liver · 2026Article
- Ampullary Neuroendocrine Tumors: Multicenter Experience and Emerging Perspectives on Endoscopic Treatment.Rambam Maimonides medical journal · 2026Article
- Prophylactic Closure of Mucosal Defect to Prevent Delayed Bleeding After Endoscopic Papillectomy.Canadian journal of gastroenterology & hepatology · 2026Article
- Clinical Outcomes of Endoscopic Resection for Large (>3 cm) Ampullary Tumors.Endoscopy international open · 2026Article
- Feasibility of pancreatic duct stent placement before endoscopic submucosal dissection for superficial duodenal neoplasms adjacent to the papilla.Clinical endoscopy · 2026Article
- Chinese clinical practice guidelines for super minimally invasive surgery of digestive tract tumors.Journal of translational internal medicine · 2025Article
- Endoscopic papillectomy for ampullary adenomas in familial adenomatous polyposis.Familial cancer · 2025Article
- Histopathologic discrepancies between endoscopic forceps biopsy and resection specimens in duodenal papillary lesions: a retrospective study.BMC gastroenterology · 2025Observational
- New Endoscopic Strategy for Ampullary Tumor and Superficial Nonampullary Duodenal Epithelial Tumor Extending Into Papillary Area.Journal of hepato-biliary-pancreatic sciences · 2025Observational
- Factors associated with delayed bleeding following ampullectomy: A retrospective cohort study.DEN open · 2025Article
- Lost ampullary opening post endoscopic submucosal dissection: EUS-guided rendezvous shows the path.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2025Article
- Risk factors for recurrence after endoscopic papillectomy in ampullary adenomas: a retrospective case-control study.Therapeutic advances in gastroenterology · 2025Article
- Effectiveness of endoscopic papillectomy with stent placement in pancreatic and bile ducts for treating duodenal papillary adenoma: a retrospective study.BMC gastroenterology · 2024Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endoscopic papillectomy (EP) is a viable therapy in ampullary lesions (AL). Many series have reported low morbidity and acceptable outcomes. We performed a systematic review with pooled analysis to assess the safety and efficacy of EP for AL. Electronic databases (Medline, Scopus and EMBASE) were searched up to September 2018. Studies that included patients with endoscopically resected AL were eligible. The rate of adverse events (AEs; primary outcome) and the rates of both technical and clinical efficacy outcomes were pooled by means of a random- or fixed-effects model to obtain a proportion with a 95% confidence interval (CI). Twenty-nine studies were included (1751 patients). The overall AE rate was 24.9%. The post-procedural pancreatitis rate was 11.9%, with the only factor affecting this outcome being prophylactic pancreatic stenting. The complete resection rate was 94.2%, with a rate of oncologically curative resection of 87.1%. The recurrence rate was 11.8% (follow-up: 9.6-84.5 months). EP is a relatively safe and effective option for AL. Our study might definitively suggest the protective role of prophylactic pancreatic stenting against post-procedural pancreatitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.