Evidence map›Paper›PMID 32212910›Full record

ArticleJournal of the American Heart Association2020

Exercise Capacity, Coronary Artery Fatty Plaque, Coronary Calcium Score, and Cardiovascular Events in Subjects With Stable Coronary Artery Disease.

Abdulaziz Malik, Jaya S Kanduri, Abdul Aziz A Asbeutah, Haitham Khraishah, Changyu Shen, Francine K Welty

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Subclinical cardiovascular disease and utility of coronary artery calcium score.International journal of cardiology. Heart & vasculature · 2021
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abdulaziz MalikDivision of Cardiovascular Medicine Department of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.
Jaya S KanduriDepartment of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.
Abdul Aziz A AsbeutahDivision of Cardiovascular Medicine Department of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.
Haitham KhraishahDepartment of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.
Changyu ShenDivision of Cardiovascular Medicine Department of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.
Francine K WeltyDivision of Cardiovascular Medicine Department of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA.

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Weight Loss, Inflammation, and Vascular RemodelingP50HL083813 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI WELTY, FRANCINE K · 2006 to 2015
$13.0M
NCATS NIH HHS UL1 TR001102NHLBI NIH HHS P50 HL083813
6 · The paper itself

Abstract

Background Aerobic exercise capacity is inversely associated with cardiovascular and all-cause mortality in men and women without coronary artery disease (CAD); however, a higher amount of vigorous exercise is associated with a J-shaped relationship in CAD patients. Therefore, the optimal type and amount of exercise for CAD patients is unclear. Coronary artery calcification (CAC) is associated with increased cardiovascular disease (CVD) events and mortality. Fatty plaque is more likely to rupture and cause coronary events than other types. We examined the association between exercise capacity, fatty plaque, CAC score and CVD events in CAD patients. Methods and Results A total of 270 subjects with stable CAD were divided into tertiles based on metabolic equivalents of task (METs) calculated from exercise treadmill testing. Self-reported exercise was obtained. Coronary computed tomographic angiography measured coronary plaque volume and CAC score. After adjustment, fatty plaque volume was not different among the 3 MET groups. For each 1 MET increase, CAC was 66.2 units lower (

Indexed as

Cardiorespiratory FitnessExercise TolerancePlaque, AtheroscleroticAdultAgedAged, 80 and overComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseCross-Sectional StudiesExercise TestFemaleHeart Disease Risk FactorsHumansMaleMiddle Agedcoronary artery calcificationcoronary artery diseasecoronary computed tomographic angiographycoronary fatty plaqueexercise capacity

Identifiers

PMID32212910
PMCPMC7428649

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.