Evidence map›Paper›PMID 32212395›Full record

Trial reportJournal of the American Geriatrics Society2020

Optimizing Retention in a Pragmatic Trial of Community-Living Older Persons: The STRIDE Study.

Thomas M Gill, Joanne M McGloin, Amy Shelton, Luann M Bianco, Eleni A Skokos, Nancy K Latham, David A Ganz, Linda V Nyquist, Robert B Wallace, Martha B Carnie and 6 more

Open access · bronzeAbstract readPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Geriatrics Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  4. Validation of a Rule-Based ICD-10-CM Algorithm to Detect Fall Injuries in Medicare Data.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Thomas M GillDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.ORCID 0000-0002-6450-0368
Joanne M McGloinDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
Amy SheltonDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
Luann M BiancoDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
Eleni A SkokosDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
Nancy K LathamBrigham and Women's Hospital, Boston, Massachusetts.
David A GanzMulticampus Program in Geriatric Medicine and Gerontology, David Geffen School of Medicine at UCLA, Los Angeles, California.
Linda V NyquistMichigan Medicine, University of Michigan, Ann Arbor, Michigan.
Robert B WallaceUniversity of Iowa, Iowa City, Iowa.
Martha B CarnieBrigham and Women's Hospital, Boston, Massachusetts.
Patricia C DykesBrigham and Women's Hospital, Boston, Massachusetts.
Lori A GoehringBrigham and Women's Hospital, Boston, Massachusetts.
Margaret DoyleDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
Peter A CharpentierDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
Erich J GreeneYale Center for Analytical Sciences, Yale School of Public Health, New Haven, Connecticut.ORCID 0000-0002-9473-830X
Katy L AraujoDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
Yale University · USBrigham and Women's Hospital · USUniversity of California, Los Angeles · USUniversity of Iowa · USUniversity of Michigan · US

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Denise Kathryn Houston · 2002 to 2026
$36.4M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Randomized Trial of a Multifactorial Fall Injury Prevention Strategy-SupplementU01AG048270 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI BHASIN, SHALENDER, GILL, THOMAS MICHAEL · 2014 to 2019
$34.8M
Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
UTMB OAIC Research Education Component (REC)P30AG024832 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI JAMES S. GOODWIN, MD, MELISSA M. MORROW · 2005 to 2026
$26.7M
TUFTS--FIELDINGP30AG031679 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI SHALENDER BHASIN · 2008 to 2026
$23.9M
Residing in the Community with Dementia at the End of Life: Understanding Hospice Use and Residential SettingP30AG028741 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ORNA INTRATOR · 2010 to 2026
$21.9M
UCLA OLDER AMERICANS INDEPENDENCE CENTERP30AG028748 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MOORE, ALISON AHERN · 2006 to 2017
$9.8M
NCATS NIH HHS UL1 TR000142NCATS NIH HHS UL1 TR001102NCATS NIH HHS UL1 TR001863NIA NIH HHS K07 AG043587NIA NIH HHS K07AG043587NIA NIH HHS P30AG013679NIA NIH HHS P30 AG021332NIA NIH HHS P30AG021332NIA NIH HHS P30 AG021342NIA NIH HHS P30AG021342NIA NIH HHS P30 AG024824NIA NIH HHS P30AG024824NIA NIH HHS P30 AG024832NIA NIH HHS P30AG024832NIA NIH HHS P30 AG028741NIA NIH HHS P30 AG028748NIA NIH HHS P30AG028748NIA NIH HHS P30 AG031679NIA NIH HHS P30AG2874106NIA NIH HHS U01 AG048270NIA NIH HHS U01AG048270NIH HHS KL2TR000113NIH HHS UL1TR000114NIH HHS UL1TR000142NIH HHS UL1TR001102
6 · The paper itself

Abstract

objectivesThe Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) study is testing the effectiveness of a multifactorial intervention to prevent serious fall injuries. Our aim was to describe procedures that were implemented to optimize participant retention; report retention yields by age, sex, clinical site, and follow-up time; provide reasons for study withdrawals; and highlight the successes and lessons learned from the STRIDE retention efforts.

designPragmatic cluster randomized trial.

settingA total of 86 primary care practices within 10 US healthcare systems.

participantsA total of 5451 community-living persons, 70 years of age or older, at high risk for serious fall injuries. MEASUREMENTS: Study outcomes were collected every 4 months by a central call center. Reconsent was required to extend follow-up beyond the originally planned 36 months.

resultsOver a median follow-up of 3.2 years (interquartile range = 2.8-3.7 y), 439 (8.1%) participants died and 600 (11.0%) withdrew their consent or did not reconsent to extend follow-up beyond 36 months, yielding rates (per 100 person-years) of deaths and withdrawals of 2.6 and 3.6, respectively. The withdrawal rate increased with advancing age, was comparable for men and women, and did not differ much by clinical site. The most common reasons for withdrawal were illness and unable to contact for reconsent at 36 months. Completion of the follow-up interviews was greater than 93% at each time point. Most participants completed all (71.8%) or all but one (9.2%) of the follow-up interviews. The most common reason for not completing a follow-up interview was unable to contact, with rates ranging from 2.8% at 40 months to 4.6% at 20 months.

conclusionCompletion of the thrice-yearly follow-up interviews in STRIDE was high, and retention of participants over 44 months exceeded the original projections. The procedures used in STRIDE, together with lessons learned, should assist other investigators who are planning or conducting large pragmatic trials of vulnerable older persons. J Am Geriatr Soc 68:1242-1249, 2020.

Indexed as

Independent LivingPrimary Health CareRisk AssessmentAccidental FallsAgedAged, 80 and overFemaleHumansInterviews as TopicLongitudinal StudiesMaleolder personspragmatic trialsretention

Identifiers

PMID32212395
PMCPMC7707554
OpenAlexW3013538214

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.