Evidence map›Paper›PMID 32211978›Full record

ArticleLung2020

Area Under the Expiratory Flow-Volume Curve (AEX): Assessing Bronchodilator Responsiveness.

Octavian C Ioachimescu, James K Stoller

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lung, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. The Challenges of Spirometric Diagnosis of COPD.Canadian respiratory journal · 2023
    Review
  4. Area under the expiratory flow-volume curve: normative values in the National Health and Nutrition Survey (NHANES) study.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Octavian C IoachimescuDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, School of Medicine, Emory University, Atlanta VA Sleep Medicine Center, 250 N Arcadia Ave, Decatur, GA, 30030, USA. oioac@yahoo.com.
James K StollerEducation Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArea under expiratory flow-volume curve (AEX) is a useful spirometric tool in stratifying respiratory impairment. The AEX approximations based on isovolumic flows can be used with reasonable accuracy when AEX is unavailable. We assessed here pre- to post-bronchodilator (BD) variability of AEX

methodsThe BD response was assessed in 4330 subjects by changes in FEV

resultsUsing standard BD criteria, 24% of subjects had a positive response. Using the new BD response categories, only 23% of subjects had a negative response; 45% minimal, 18% mild, 9% moderate, and 5% had a marked BD response. Mean percent change of the square root AEX

conclusionsMean pre- to post-BD variability of AEX

Indexed as

AgedBronchodilator AgentsExhalationFemaleForced Expiratory VolumeHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveRetrospective StudiesSpirometryVital CapacityBronchodilator AgentsArea under flow–volume curveBronchodilator responseLung functionLung volumesSpirometry

Identifiers

PMID32211978
PMCPMC7242267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.