ReviewDer Radiologe2020
State-of-the-art imaging for diagnosis of metastatic bone disease.
Review in Der Radiologe, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Incidence, epidemiology, radiology, and classification of metastatic spine tumors: WFNS Spine Committee recommendations.Neurosurgical review · 2024Pooled it
- Artificial intelligence applied to musculoskeletal oncology: a systematic review.Skeletal radiology · 2022Pooled it
- Dual-energy CT virtual non-calcium imaging for differentiating pathologic from non-pathologic femoral fractures: a study of inexperienced non-radiologist readers.Skeletal radiology · 2026Article
- A Fully Automated Pipeline for Vertebral Structural Assessment From Medical Images. Application Under Metastatic Conditions.International journal for numerical methods in biomedical engineering · 2026Article
- Cost-effectiveness analysis of a bone metastasis cancer board for skeletal-related events of breast cancer.Japanese journal of clinical oncology · 2026Article
- Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta-analysis of a confusion matrix.Oncology letters · 2026Article
- Differentiating between benign and malignant bone lesions: The value of using SPECT/CT.Radiology case reports · 2026Article
- Benign and malignant bone lesion diagnosis based on self-supervised and radiomics fusion using SPECT/CT images.Journal of bone oncology · 2025Article
- Application value of bone metabolism and immune cell indicators in screening for tumor bone metastasis: a retrospective study.American journal of cancer research · 2025Article
- Image-Guided Musculoskeletal Interventional Radiology in the Personalised Management of Musculoskeletal Tumours.Journal of personalized medicine · 2024Review
- Bone marrow magnetic resonance imaging (MRI): morphological and functional features from reconversion to infiltration.Quantitative imaging in medicine and surgery · 2024Review
- Review
- Artificial Intelligence in Detection, Management, and Prognosis of Bone Metastasis: A Systematic Review.Cancers · 2024Review
- An objective measure of response on whole-body MRI in metastatic hormone sensitive prostate cancer treated with androgen deprivation therapy, external beam radiotherapy, and radium-223.The British journal of radiology · 2024Article
- diagnostic approach to bone metastasis of unknown origin: a systematic review.Orthopedic reviews · 2024Article
- Risk factor analysis and predictive model construction for bone metastasis in newly diagnosed malignant tumor patients.American journal of translational research · 2024Article
- Molecular imaging of bone metastasis.Journal of bone oncology · 2023Review
- Risk Factors, Patterns, and Distribution of Bone Metastases and Skeletal-Related Events in High-Risk Breast Cancer Patients.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Review
- Mortality factors in recurrent parathyroid cancer: a pooled analysis.Journal of bone and mineral metabolism · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metastatic bone disease (MBD) is common-it is detected in up to 65-75% of patients with breast or prostate cancer, in over 35% of patients with lung cancer; and almost all patients with symptomatic multiple myeloma have focal lesions or a diffuse bone marrow infiltration. Metastatic bone disease can cause a variety of symptoms and is often associated with a poorer prognosis, with high social and health-care costs. Population-based cohort studies confirm significantly increased health-care utilization costs in patients presenting with cancer with MBD compared with those without MBD. The prolonged survival of patients with bone metastasis thanks to advances in therapy presents an opportunity for better treatments for this patient cohort. Early and accurate diagnosis of bone metastases is therefore crucial. The patterns and presentation of MBD are quite heterogeneous and necessitate good knowledge of the possibilities and limitations of each imaging modality. Here, we review the state-of-the-art imaging techniques, assess the need for evidence-based and cost-effective patient care pathways, and advocate multidisciplinary management based on collaborations between orthopedic surgeons, pathologists, oncologists, radiotherapists, and radiologists aimed at improving patient outcomes. Radiologists play a key role in this multidisciplinary approach to decision-making through correlating the tumor entity, the tumor biology, the impact on the surrounding tissues and progression, as well as the overall condition of the patient. This approach helps to choose the best patient-tailored imaging plan advocating a "choose wisely" strategy throughout the initial diagnosis, minimally invasive treatment procedures, as well as follow-up care plans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.