ArticleJournal of experimental botany2020
Four bottlenecks restrict colonization and invasion by the pathogen Ralstonia solanacearum in resistant tomato.
Article in Journal of experimental botany, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 84 citations in OpenAlex.
- Invasion of Clavibacter michiganensis into the Xylem and Surrounding Tissues Drives Histological Alterations and Disease Development in Tomato.The plant pathology journal · 2026Article
- Auxin-responsive SlXTH3 promotes Ralstonia solanacearum infection by modulating lateral root development and root immunity in tomato.Plant cell reports · 2026Article
- A genome-scale metabolic model of a pathosystem sheds light on bacterial wilt.Plant physiology · 2026Article
- Ralstonia pseudosolanacearum PhcQ Controls Quorum Sensing-Dependent Phenotypes by Binding PhcA and Maintaining Its Protein Stability.Molecular plant pathology · 2026Article
- Bayesian Pairwise Compositional Lotka-Volterra Modeling Infers Potential Rhizosphere Microbial Suppressors of Ralstonia pseudosolanacearum.The plant pathology journal · 2026Article
- Tissue-specific experimental evolution reveals adaptive trade-offs in the plant vascular pathogen Clavibacter michiganensis.The ISME journal · 2026Article
- The Effector RipAW Enhances Ralstonia solanacearum Invasion in Arabidopsis via CBP60g/SARD1-Dependent and -Independent Pathways.Molecular plant pathology · 2026Article
- The Ralstonia solanacearum catalase-peroxidase KatG is crucial to survive environmental stresses and also plays a role in plant infection.Scientific reports · 2025Article
- The CAPE1 peptide confers resistance against bacterial wilt in tomato.Journal of experimental botany · 2025Article
- Intraspecific Grafting of Tomatoes: Impact of Disease-Resistant Rootstocks on Fusarium Wilt Prevention, Plant Growth, and Fruit Quality under Naturally Infested Field Conditions.The plant pathology journal · 2025Article
- The influence of the polyamine synthesis pathways onMicrobiology (Reading, England) · 2025Article
- Root exudate monosaccharides modulate the pathogenicity ofFrontiers in microbiology · 2025Article
- Shk (a histidine kinase) positively regulates the virulence ofFrontiers in microbiomes · 2025Article
- Strategies utilized by plants to defend againstFrontiers in plant science · 2025Review
- A Ralstonia solanacearum type III effector alters the actin and microtubule cytoskeleton to promote bacterial virulence in plants.PLoS pathogens · 2024Article
- Quantitative Trait Loci Mapping for Bacterial Wilt Resistance and Plant Height in Tomatoes.Plants (Basel, Switzerland) · 2024Article
- Effects of plant tissue permeability on invasion and population bottlenecks of a phytopathogen.Nature communications · 2024Article
- TomatoFrontiers in plant science · 2024Article
- ETI signaling nodes are involved in resistance of Hawaii 7996 toPlant signaling & behavior · 2023Article
- Gene expression changes throughout the life cycle allow a bacterial plant pathogen to persist in diverse environmental habitats.PLoS pathogens · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ralstonia solanacearum is a bacterial vascular pathogen causing devastating bacterial wilt. In the field, resistance against this pathogen is quantitative and is available for breeders only in tomato and eggplant. To understand the basis of resistance to R. solanacearum in tomato, we investigated the spatio-temporal dynamics of bacterial colonization using non-invasive live monitoring techniques coupled to grafting of susceptible and resistant varieties. We found four 'bottlenecks' that limit the bacterium in resistant tomato: root colonization, vertical movement from roots to shoots, circular vascular bundle invasion, and radial apoplastic spread in the cortex. Radial invasion of cortical extracellular spaces occurred mostly at late disease stages but was observed throughout plant infection. This study shows that resistance is expressed in both root and shoot tissues, and highlights the importance of structural constraints to bacterial spread as a resistance mechanism. It also shows that R. solanacearum is not only a vascular pathogen but spreads out of the xylem, occupying the plant apoplast niche. Our work will help elucidate the complex genetic determinants of resistance, setting the foundations to decipher the molecular mechanisms that limit pathogen colonization, which may provide new precision tools to fight bacterial wilt in the field.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.