ReviewNatural product reports2020
Secondary metabolites from hypocrealean entomopathogenic fungi: novel bioactive compounds.
Review in Natural product reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 119 citations in OpenAlex.
- Integrated molecular networking-guided discovery of antimicrobial secondary metabolites fromRSC advances · 2026Article
- Delivery strategies for entomopathogenic fungi in crop pest management: a review.Pest management science · 2026Review
- Microbiota variation inMicrobiology spectrum · 2026Article
- A biosynthetic survey of hypocrealean biocontrol fungi.Nature chemical biology · 2026Article
- Screening and Pathogenic Potential of Entomopathogenic Fungi Against Dactylopius opuntiae (Cockerell. 1929) (Hemiptera: Dactylopiidae).Neotropical entomology · 2026Article
- Entomopathogenic fungi as potential biological control agents against basal stem rot in oil palm plantations of Sabah, Malaysia.Scientific reports · 2026Article
- Novel Endophytic Fungi fromMicroorganisms · 2026Article
- Paraisariamides: Cycloheptapeptide Toxins from Entomopathogenic Fungi (Journal of natural products · 2026Article
- Bioactive metabolites from cultures of the entomopathogenic fungusRSC advances · 2026Article
- A metabolomics approach to target the effect of histone protein methyltransferase-specific probe UNC1999 on cryptic metabolites in an endophytic fungusFrontiers in microbiology · 2026Article
- Article
- Effects of Insect Cuticular Compounds on Appressorium Formation and Metabolic Activity inJournal of fungi (Basel, Switzerland) · 2025Article
- Laboratory evaluation of Beauveria bassiana strain ATCC74040 as a potential biocontrol agent of Aculops lycopersici.Scientific reports · 2025Article
- Biological Evaluation and Potential Applications of Secondary Metabolites from Fungi Belonging to the Cordycipitaceae Family with a Focus onJournal of fungi (Basel, Switzerland) · 2025Review
- Analysis of Toxic Components in Secondary Metabolites of Entomopathogenic FungiMicroorganisms · 2025Article
- An endosymbiotic origin of the crimson pigment from the lac insect.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Entomopathogenic fungi: insights into recent understanding.World journal of microbiology & biotechnology · 2025Review
- Bioactive polyketides from cultures of the entomopathogenic fungusRSC advances · 2025Article
- Visualizing Oral Infection Dynamics ofJournal of fungi (Basel, Switzerland) · 2025Article
- Taxonomic Study of Sixteen Unrecorded and Five New Species ofMycobiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Covering: 2014 up to the third quarter of 2019 Entomopathogens constitute a unique, specialized trophic subgroup of fungi, most of whose members belong to the order Hypocreales (class Sordariomycetes, phylum Ascomycota). These Hypocrealean Entomopathogenic Fungi (HEF) produce a large variety of secondary metabolites (SMs) and their genomes rank highly for the number of predicted, unique SM biosynthetic gene clusters. SMs from HEF have diverse roles in insect pathogenicity as virulence factors by modulating various interactions between the producer fungus and its insect host. In addition, these SMs also defend the carcass of the prey against opportunistic microbial invaders, mediate intra- and interspecies communication, and mitigate abiotic and biotic stresses. Thus, these SMs contribute to the role of HEF as commercial biopesticides in the context of integrated pest management systems, and provide lead compounds for the development of chemical pesticides for crop protection. These bioactive SMs also underpin the widespread use of certain HEF as nutraceuticals and traditional remedies, and allowed the modern pharmaceutical industry to repurpose some of these molecules as life-saving human medications. Herein, we survey the structures and biological activities of SMs described from HEF, and summarize new information on the roles of these metabolites in fungal virulence.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.