Evidence map›Paper›PMID 32211607›Full record

ArticleMaterials today. Bio2020

Antioxidant mesoporous Ce-doped bioactive glass nanoparticles with anti-inflammatory and pro-osteogenic activities.

Kai Zheng, Elisa Torre, Alessandra Bari, Nicola Taccardi, Clara Cassinelli, Marco Morra, Sonia Fiorilli, Chiara Vitale-Brovarone, Giorgio Iviglia, Aldo R Boccaccini

Open access · goldAbstract read
In one paragraph

Article in Materials today. Bio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 147 citations in OpenAlex.

  1. Pooled it
  2. Porous Ag-Cu-CeOBiochemistry and biophysics reports · 2026
    Article
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  4. Article
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  7. Article
  8. Article
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  10. Article
  11. Article
  12. Article
  13. Review
  14. Impact of Vitamin DJournal of functional biomaterials · 2025
    Article
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  16. Review
  17. Article
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Kai ZhengInstitute of Biomaterials, University of Erlangen-Nuremberg, Erlangen, Germany.
Elisa TorreNobil Bio Ricerche Srl, Portacomaro D'Asti, Italy.
Alessandra BariDepartment of Applied Science and Technology, Politecnico di Torino, Turin, Italy.
Nicola TaccardiInstitute of Chemical Reaction Engineering, University of Erlangen-Nuremberg, Erlangen, Germany.
Clara CassinelliNobil Bio Ricerche Srl, Portacomaro D'Asti, Italy.
Marco MorraNobil Bio Ricerche Srl, Portacomaro D'Asti, Italy.
Sonia FiorilliDepartment of Applied Science and Technology, Politecnico di Torino, Turin, Italy.
Chiara Vitale-BrovaroneDepartment of Applied Science and Technology, Politecnico di Torino, Turin, Italy.
Giorgio IvigliaNobil Bio Ricerche Srl, Portacomaro D'Asti, Italy.
Aldo R BoccacciniInstitute of Biomaterials, University of Erlangen-Nuremberg, Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEPolitecnico di Torino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesoporous bioactive glass nanoparticles (MBGNs) are emerging biomaterials for bone repair/regeneration, considering their favorable pro-osteogenic and proangiogenic activities. To further improve their therapeutic effects, the endowment of MBGNs with additional antioxidant properties is of particular interest to target oxidative stress related to bone remodeling and diseases. To this end, we developed antioxidant cerium-containing MBGNs (Ce-MBGNs) (particle size of 100-300 ​nm) by using a postimpregnation strategy to incorporate Ce, through which the shape, pore structure, and dispersity of the nanoparticles were preserved. The incorporated amount of Ce could be tailored by adjusting the concentration of the Ce precursor solution. When impregnated at a relatively low temperature (20 ​°C), Ce-MBGNs containing either 1.8 or 2.8 ​mol% of Ce were produced, while the formation of by-product cerium oxide nanoparticles (nanoceria) could be avoided. In both developed Ce-MBGNs, the concentration of Ce

Indexed as

Anti-inflammatoryAntioxidantBioactive particlesCeriumPro-osteogenesisSurface modification

Identifiers

PMID32211607
PMCPMC7083763
OpenAlexW3000288759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.