ArticleJournal of immunology research2020
Diagnostic Sensitivity of NLR and PLR in Early Diagnosis of Gastric Cancer.
Article in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers, 2 of them syntheses that pooled it.
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Who cites it
113 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Prognostic value of inflammatory markers NLR, PLR, and LMR in gastric cancer patients treated with immune checkpoint inhibitors: a meta-analysis and systematic review.Frontiers in immunology · 2024Pooled it
- Value of preoperative peripheral blood inflammation markers in predicting prognosis after radical gastric cancer surgery.Scientific reports · 2026Article
- Biomarkers in Gastric Cancer: Blood Biomarkers, Liquid Biopsy, Artificial Intelligence, and Risk-Stratified Care.Cancers · 2026Review
- Osteosarcopenia as a prognostic indicator of gastric cancer compared with established nutritional markers.Langenbeck's archives of surgery · 2026Article
- Dynamic systemic immune-inflammation index predicts survival after neoadjuvant immunotherapy in gastric cancer: A multicenter study.iScience · 2026Article
- Prognostic value of Neutrophil-to-Lymphocyte Ratio (NLR) in patients with Leptomeningeal Metastasis (LM) from solid tumors.BMC cancer · 2026Article
- The prognostic value analysis of PIV, PLR, LMR, NPR, and NLR in hilar cholangiocarcinoma.BMC cancer · 2026Article
- PHGDH knockdown activates autophagic flux to suppress migration and invasion of gastric cancer cells.Translational cancer research · 2026Article
- The Association of Neutrophil-To-Lymphocyte and Platelet-To-Lymphocyte Ratios With Distant Metastasis in Vietnamese Gastric Cancer Patients.Cancer informatics · 2026Article
- Pretreatment neutrophil-lymphocyte ratio and platelet-lymphocyte ratio as prognostic biomarkers for neuroblastoma risk stratification.Frontiers in immunology · 2026Article
- Predictability of peripheral blood inflammatory markers in prediction of lymph node metastasis in gastric cancer.Therapeutic advances in gastroenterology · 2026Article
- Association of systemic inflammatory indices with gastrointestinal tumors: evidence from NHANES and a hospital-based cohort.Frontiers in medicine · 2026Article
- A novel combined neutrophil-platelet score for diagnosing complicated appendicitis: a retrospective and prospective cohort study.Acta cirurgica brasileira · 2026Article
- Can Albumin/Lymphocyte Ratio and MPV/Lymphocyte Ratio Serve as New Inflammatory Biomarkers in Patients With Hyperemesis Gravidarum?Journal of clinical laboratory analysis · 2025Article
- Article
- Associations between complete-blood-count-derived inflammatory markers and gastric ulcer: A cross-sectional study.World journal of gastroenterology · 2025Article
- The unique characteristics and risk factors of enlarged perivascular spaces in pediatric moyamoya disease.Quantitative imaging in medicine and surgery · 2025Article
- Association Between Platelet-to-Lymphocyte Ratio and Insulin Resistance in Cancer Survivors: A Cross-Sectional Study Based on the NHANES 2005 - 2018.World journal of oncology · 2025Article
- Current and evolving practices of carbohydrate antigens in gastric cancer: a narrative review.Translational cancer research · 2025Review
53 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR) are markers of systemic inflammation. However, there is little evidence of the value of inflammation in the early diagnosis of gastric cancer (GC). A total of 2,606 patients diagnosed with GC in the past three years and 3,219 healthy controls over the same period were included in this study. Peripheral blood samples were obtained to analyze the NLR, PLR, carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9). The optimal cutoff levels for the NLR and PLR were defined by receiver operating characteristic (ROC) curve analysis (NLR = 2.258, PLR = 147.368). The value of different biomarkers for diagnosing GC was compared by the area under the curve (AUC). The NLR and PLR showed diagnostic sensitivity in GC (AUC = 0.715, AUC = 0.707). Using the Bonferroni correction, the NLR and PLR were superior to CEA and CA19-9 in the diagnosis of GC (
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