ReviewFrontiers in pediatrics2019
Tuberculosis and HIV-An Update on the "Cursed Duet" in Children.
Review in Frontiers in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Prevalence of HIV-associated nephropathy in children: a systematic review with meta-analysis of studies published between 2004 and 2019.Pediatric nephrology (Berlin, Germany) · 2026Pooled it
- Mortality and associated factors among children with the double burden of human immunodeficiency virus and tuberculosis in African countries: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Pooled it
- Trial
- Case report from a pediatric multidrug-resistant tuberculosis case with Tsukamurella co-infection identified by whole-genome sequencing: a diagnostic and therapeutic challenge.BMC infectious diseases · 2026Article
- Linking Children and Adolescents With TB Disease to HIV Services in 16 PEPFAR-supported High TB/HIV-Burden Countries in Sub-Saharan Africa, October 2018-September 2022.The Pediatric infectious disease journal · 2026Article
- Tertiary-care management of TB/HIV co-infection in Port Harcourt, Nigeria: A retrospective cohort analysis.PloS one · 2026Article
- Assessing the performance of longitudinal T-lymphocytes as biomarkers of immune recovery in HIV-infected children with or without TB co-infection.Journal of applied statistics · 2026Article
- Temporal changes in pediatric tuberculosis incidence in Rio de Janeiro (2010-2023): An analysis using the Joinpoint model.PloS one · 2026Article
- Characteristics and mortality of children living with HIV/TB coinfection in a tertiary hospital in a resource-limited setting.BMC infectious diseases · 2025Observational
- Unmasking Bacillus Calmette-Guérin Immune Reconstitution Inflammatory Syndrome in a Perinatal HIV Transmission-A Case Report.Tropical medicine and infectious disease · 2025Article
- Article
- Factors associated with in-hospital mortality in HIV-infected children treated for tuberculous meningitis hydrocephalus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Surgery for bronchiectasis in children living with HIV: A case series from a low- to middle-income country.African journal of thoracic and critical care medicine · 2024Article
- A critical perspective on paediatric pulmonary tuberculosis and diagnostic advancements.African journal of thoracic and critical care medicine · 2024Article
- Morbidity and mortality in tuberculosis associated immune reconstitution inflammatory syndrome in children living with HIV: A narrative review.Journal of clinical tuberculosis and other mycobacterial diseases · 2023Article
- The changing characteristics of a cohort of children and adolescents living with HIV at antiretroviral therapy initiation in Asia.PloS one · 2023Article
- Article
- Tuberculosis in children with severe acute malnutrition.Expert review of respiratory medicine · 2022Review
- The COVID-19/Tuberculosis Syndemic and Potential Antibody Therapy for TB Based on the Lessons Learnt From the Pandemic.Frontiers in immunology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
HIV and tuberculosis (TB) often occur together with each exacerbating the other. Improvements in vertical transmission prevention has reduced the number of HIV-infected children being born and early antiretroviral therapy (ART) protects against tuberculosis. However, with delayed HIV diagnosis, HIV-infected infants often present with tuberculosis co-infection. The number of HIV exposed uninfected children has increased and these infants have high exposure to TB and may be more immunologically vulnerable due to HIV exposure
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.