Evidence map›Paper›PMID 32211344›Full record

ReviewFrontiers in cellular and infection microbiology2020

Secretion and Delivery of Intestinal Pathogenic

Christian Rueter, Martina Bielaszewska

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 2 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Virulence · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
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  14. Predicting clinical outcome ofMicrobial genomics · 2025
    Article
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  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Christian RueterCenter for Molecular Biology of Inflammation (ZMBE), Institute of Infectiology, University of Muenster, Münster, Germany.
Martina BielaszewskaNational Institute of Public Health, Reference Laboratory for E. coli and Shigellae, Prague, Czechia.
Institute of Molecular Biology · DENational Institute of Public Health · CZ

Funding

Using anti-inflammatory bacterial proteins to treat psoriasisR56AR072594 · NIAMS · KANSAS STATE UNIVERSITY · PI HARDWIDGE, PHILIP ROSS · 2018 to 2018
$282k
NIAMS NIH HHS R56 AR072594
6 · The paper itself

Abstract

Outer membrane vesicles (OMVs) are nanoscale proteoliposomes secreted from the cell envelope of all Gram-negative bacteria. Originally considered as an artifact of the cell wall, OMVs are now recognized as a general secretion system, which serves to improve the fitness of bacteria and facilitate bacterial interactions in polymicrobial communities as well as interactions between the microbe and the host. In general, OMVs are released in increased amounts from pathogenic bacteria and have been found to harbor much of the contents of the parental bacterium. They mainly encompass components of the outer membrane and the periplasm including various virulence factors such as toxins, adhesins, and immunomodulatory molecules. Numerous studies have clearly shown that the delivery of toxins and other virulence factors via OMVs essentially influences their interactions with host cells. Here, we review the OMV-mediated intracellular deployment of toxins and other virulence factors with a special focus on intestinal pathogenic

Indexed as

AnimalsBacterial Outer MembraneBacterial Secretion SystemsBacterial ToxinsEnterohemorrhagic Escherichia coliEnterotoxigenic Escherichia coliEnterotoxinsEscherichia coli InfectionsHumansIntestinesProtein TransportProteolipidsStress, PhysiologicalVirulenceVirulence FactorsBacterial Secretion SystemsBacterial ToxinsEnterotoxinsProteolipidsproteoliposomesVirulence FactorsEHECETECintestinal pathogenic Escherichia coliouter membrane vesiclestoxinsvirulence factors

Identifiers

PMID32211344
PMCPMC7068151
OpenAlexW3009949103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.