Evidence map›Paper›PMID 32210959›Full record

ArticleFrontiers in immunology2020

Altered Monocyte and Langerhans Cell Innate Immunity in Patients With Recurrent Respiratory Papillomatosis (RRP).

Mohd Israr, James A DeVoti, Fung Lam, Allan L Abramson, Bettie M Steinberg, Vincent R Bonagura

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
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  8. Increased Abundances of CD16Biomedicines · 2022
    Article
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  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Biologics for the Treatment of Recurrent Respiratory Papillomatosis.Otolaryngologic clinics of North America · 2021
    Review
  18. Article
  19. Involvement of TLR9 in priming the immune response in oral papillomatosis induced by low-risk HPV.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mohd IsrarBarbara and Donald Zucker School of Medicine at Hofstra/Northwell, Feinstein Institutes for Medical Research, Manhasset, NY, United States.
James A DeVotiBarbara and Donald Zucker School of Medicine at Hofstra/Northwell, Feinstein Institutes for Medical Research, Manhasset, NY, United States.
Fung LamBarbara and Donald Zucker School of Medicine at Hofstra/Northwell, Feinstein Institutes for Medical Research, Manhasset, NY, United States.
Allan L AbramsonDepartment of Otolaryngology, Long Island Jewish Medical Center, Barbara and Donald Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, NY, United States.
Bettie M SteinbergBarbara and Donald Zucker School of Medicine at Hofstra/Northwell, Feinstein Institutes for Medical Research, Manhasset, NY, United States.
Vincent R BonaguraBarbara and Donald Zucker School of Medicine at Hofstra/Northwell, Feinstein Institutes for Medical Research, Manhasset, NY, United States.
Feinstein Institute for Medical Research · USLong Island Jewish Medical Center · USCohen Children's Medical Center · US

Funding

HPV-Specific, Immune Suppression in Patients with RRPR01DE017227 · NIDCR · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI BONAGURA, VINCENT ROBERT · 2006 to 2017
$4.5M
Reprogramming Host Immune Responses to Cure or Control Persistent HPV InfectionR21AI105987 · NIAID · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI BONAGURA, VINCENT ROBERT · 2013 to 2014
$589k
NIAID NIH HHS R21 AI105987NIDCR NIH HHS R01 DE017227
6 · The paper itself

Abstract

The micromilieu within respiratory papillomas supports persistent human papillomavirus (HPV) infection and disease recurrence in patients with recurrent respiratory papillomatosis (RRP). These patients show polarized (T

Indexed as

AlphapapillomavirusCell DifferentiationCells, CulturedCytokinesHumansImmune ToleranceImmunity, InnateLangerhans CellsNeoplasm Recurrence, LocalPapillomavirus InfectionsPrecancerous ConditionsRespiratory Tract InfectionsSkinTh2 CellsT-Lymphocytes, RegulatoryTumor MicroenvironmentCytokineshuman papillomaviruses (HPVs) types 6 and type 11innate immunityLangerhans cellmonocytePGE2recurrent respiratory papillomatosis

Identifiers

PMID32210959
PMCPMC7076114
OpenAlexW3011436447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.