Evidence map›Paper›PMID 32210813›Full record

ArticleFrontiers in pharmacology2020

Structure-Function of the High Affinity Substrate Binding Site (S1) of Human Norepinephrine Transporter.

Prerna Jha, Lotten Ragnarsson, Richard J Lewis

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Uptake Patterns of Peripheral Ganglia onEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Two Lignan Glycosides fromPharmaceuticals (Basel, Switzerland) · 2022
    Article
  7. Novel Molecular Targets of Antidepressants.Molecules (Basel, Switzerland) · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Prerna JhaInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Lotten RagnarssonInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Richard J LewisInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human norepinephrine transporter (hNET) is a member of the neurotransmitter/sodium symporter family, which also includes the neuronal monoamine transporters for serotonin (SERT) and dopamine (DAT). Its involvement in chronic pain and many neurological disorders underlies its pharmaceutical importance. Using the X-ray crystal structures of the human serotonin transporter (hSERT) (PDB 5I6X) and

Indexed as

docking guided mutagenesismolecular modelingmonoamine transporternoradrenaline uptakestructural determinants

Identifiers

PMID32210813
PMCPMC7066499
OpenAlexW3009194460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.