Evidence map›Paper›PMID 32210802›Full record

ArticleFrontiers in pharmacology2020

Jiang Tang Xiao Ke Granule Protects Hepatic Tissue of Diabetic Mice Through Modulation of Insulin and Ras Signaling - A Bioinformatics Analysis of MicroRNAs and mRNAs Network.

Ying Bai, Xueli Bao, Guangjian Jiang, Dongyu Ge, Weipeng He, Dandan Zhao, Yi Zhang, Ruijuan Dong, Jing Hua, Nan Yang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Frontiers in immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Ying BaiCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Xueli BaoCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Guangjian JiangCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Dongyu GeCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Weipeng HeCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Dandan ZhaoCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Yi ZhangCollege of City Management, Beijing Open University, Beijing, China.
Ruijuan DongCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Jing HuaThird Affiliated Hospital, Beijing University of Chinese Medicine, Beijing, China.
Nan YangKennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom.
Fangfang MoCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Sihua GaoCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Beijing University of Chinese Medicine · CNBeijing Open University · CNUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the impact of JTXK granule on the miRNA expression profiles in hepatic tissue of diabetic mice, and to explore the molecular targets and associated signaling pathways of JTXK granule in its anti-diabetic effect.

methodsEight mice were randomly selected as normal group fed with chow diet. Then high fat diet was used to induce diabetic model, and the mice were subsequently divided into JTXK-treated group (J group,

resultsThe blood glucose level in J group was significantly lower than M group (

conclusionJTXK granule exerts anti-diabetic effect in hepatic tissue of diabetic mice by modulating miRNAs and mRNAs network.

Indexed as

anti-diabetic effectbioinformatic analysisdiabetes mellitusJiang Tang Xiao Ke GranulemicroRNAs

Identifiers

PMID32210802
PMCPMC7067923
OpenAlexW3010134814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.