Evidence map›Paper›PMID 32210797›Full record

ArticleFrontiers in pharmacology2020

Shenlian Extract Against Myocardial Injury Induced by Ischemia Through the Regulation of NF-κB/IκB Signaling Axis.

Yuan Guo, Qing Yang, Xiao-Gang Weng, Ya-Jie Wang, Xue-Qi Hu, Xiao-Jun Zheng, Yu-Jie Li, Xiao-Xin Zhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuan GuoPharmacokinetics Laboratory, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Qing YangPharmacokinetics Laboratory, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Xiao-Gang WengPharmacokinetics Laboratory, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Ya-Jie WangPharmacokinetics Laboratory, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Xue-Qi HuCollege of Pharmacy, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Xiao-Jun ZhengPharmacy Department, First Hospital of Shanxi Medical University, Taiyuan, China.
Yu-Jie LiPharmacokinetics Laboratory, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Xiao-Xin ZhuPharmacokinetics Laboratory, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic heart disease (IHD), caused predominantly by atherosclerosis, is a leading cause of global mortality. Our previous studies showed that Shenlian extract (SL) could prevent the formation of atherosclerosis and enhance the stability of atherosclerotic plaques. To further investigate the protective effects of SL on myocardial ischemic injury and its possible mechanisms, anesthetized dogs,

Indexed as

inflammationischemic heart disease (IHD)myocardial ischemic injuryNF-κB signaling pathwayShenlian extract (SL)

Identifiers

PMID32210797
PMCPMC7069067

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.