Evidence map›Paper›PMID 32210728›Full record

ArticleInternational journal of biological sciences2020

Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.

Xiaohong Deng, Jingjing Liu, Lantao Liu, Xianjun Sun, Jianhua Huang, Jingcheng Dong

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 111 citations in OpenAlex.

  1. Review
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  6. Mitochondrial Calcium Signaling in Hepatocyte Health and Disease.Cold Spring Harbor perspectives in biology · 2026
    Review
  7. Bioactive Flavonoids fromDrug design, development and therapy · 2026
    Review
  8. Increasing autophagy activity suppressesAmerican journal of cancer research · 2026
    Article
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  12. Review
  13. Article
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  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xiaohong DengDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
Jingjing LiuDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
Lantao LiuDepartment of Interventional Radiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200050, China.
Xianjun SunDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
Jianhua HuangDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
Jingcheng DongDepartment of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
Fudan University · CNHuashan Hospital · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baicalein (BA), a natural compound extracted from

Indexed as

ApoptosisAutophagyA549 CellsAMP-Activated Protein KinasesAnimalsCell Line, TumorCell SurvivalCytoplasmDynaminsFlavanonesHumansLentivirusLung NeoplasmsMaleMembrane Potential, MitochondrialMiceAMP-Activated Protein KinasesbaicaleinDNM1L protein, humanDnm1l protein, mouseDynaminsFlavanonesReactive Oxygen SpeciesAMPKapoptosisautophagybaicaleinmitochondrial fission

Identifiers

PMID32210728
PMCPMC7085231
OpenAlexW3012938710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.