Evidence map›Paper›PMID 32210718›Full record

ArticleInternational journal of medical sciences2020

Adenine inhibits growth of hepatocellular carcinoma cells via AMPK-mediated S phase arrest and apoptotic cascade.

Wei-Wen Su, Jen-Yu Huang, Han-Min Chen, Jiun-Tsai Lin, Shao-Hsuan Kao

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. The multifaceted role of 3-methyladenine in cancer therapy.Journal of physiology and biochemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wei-Wen SuDivision of Gastroenterology, Department of Internal Medicine, Changhua Christian Hospital, Changhua 50006, Taiwan.
Jen-Yu HuangInstitute of Biochemistry, Microbiology, and Immunology, Chung Shan Medical University, Taichung 40201, Taiwan.
Han-Min ChenInstitute of Applied Science and Engineering, Catholic Fu Jen University, New Taipei 24205, Taiwan.
Jiun-Tsai LinEnergenesis Biomedical Co. Ltd., Taipei 11492, Taiwan.
Shao-Hsuan KaoInstitute of Biochemistry, Microbiology, and Immunology, Chung Shan Medical University, Taichung 40201, Taiwan.
Chung Shan Medical University · TWChanghua Christian Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenineAMP-Activated Protein KinasesApoptosisCarcinoma, HepatocellularCell CycleDrug Evaluation, PreclinicalHep G2 CellsHumansLiver NeoplasmsAdenineAMP-Activated Protein KinasesadenineAMPKapoptosisBaxhepatocellular cellp21p53

Identifiers

PMID32210718
PMCPMC7085215
OpenAlexW3012587927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.