Evidence map›Paper›PMID 32210716›Full record

ReviewInternational journal of medical sciences2020

Exosomes from Human Periapical Cyst-MSCs: Theranostic Application in Parkinson's Disease.

Marco Tatullo, Benedetta Marrelli, Maria Josephine Zullo, Bruna Codispoti, Francesco Paduano, Caterina Benincasa, Francesco Fortunato, Salvatore Scacco, Barbara Zavan, Tiziana Cocco

Open access · goldAbstract readReview
In one paragraph

Review in International journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Marco TatulloMarrelli Health - Tecnologica Research Institute, Biomedical Section, Street E. Fermi, Crotone, Italy.
Benedetta MarrelliMarrelli Health - Tecnologica Research Institute, Biomedical Section, Street E. Fermi, Crotone, Italy.
Maria Josephine ZulloDepartment of Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland.
Bruna CodispotiMarrelli Health - Tecnologica Research Institute, Biomedical Section, Street E. Fermi, Crotone, Italy.
Francesco PaduanoMarrelli Health - Tecnologica Research Institute, Biomedical Section, Street E. Fermi, Crotone, Italy.
Caterina BenincasaMarrelli Health - Tecnologica Research Institute, Biomedical Section, Street E. Fermi, Crotone, Italy.
Francesco FortunatoDepartment of Neurological Sciences, University of Catanzaro "Magna Graecia", Italy.
Salvatore ScaccoDepartment of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari "Aldo Moro", Italy.
Barbara ZavanDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Tiziana CoccoDepartment of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari "Aldo Moro", Italy.
Sechenov University · RUUniversity of Bari Aldo Moro · ITMagna Graecia University · ITUniversity of Ferrara · ITUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The scientific community continuously strives to get new disease models, to discover early markers or novel therapeutic approaches, improving the diagnosis and prognosis of several human pathologies. Parkinson's Disease (PD) is characterized by a long asymptomatic phase, characterized by a selective loss of dopaminergic neurons. Recently, the human Periapical Cyst-Mesenchymal Stem Cells (hPCy-MSCs) have been differentiated in functional dopaminergic neurons: such oral-derived MSCs and the hPCy-MSCs-derived exosomes may represent a strategic and useful

Indexed as

Circadian RhythmExosomesMesenchymal Stem CellsParkinson DiseaseRadicular CystHumansModels, BiologicalPrecision Medicinecircadian rhythmexosomesParkinson's Disease

Identifiers

PMID32210716
PMCPMC7085217
OpenAlexW3012572902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.