ArticleClinical, cosmetic and investigational dermatology2020
Clinical Assessment of New Topical Cream Containing Two Essential Oils Combined with Tretinoin in the Treatment of Acne.
Article in Clinical, cosmetic and investigational dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Effect of Rosemary Cream on Episiotomy Wound Healing in Primiparous Women: A Randomized Clinical Trial.BMC complementary medicine and therapies · 2022Trial
- Article
- The Therapeutic Potential of Essential Oils in Managing Inflammatory Skin Conditions: A Scoping Review.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Stability Profile and Clinical Evaluation of an Innovative Hydrogel Containing Polymeric Micelles as Drug Delivery Systems with Oregano Essential Oil against Fibroepithelial Polyps.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Cutaneous Polymeric-Micelles-Based Hydrogel ContainingPharmaceuticals (Basel, Switzerland) · 2023Article
- Synergistic Antibacterial Effect of Ethyl Acetate Fraction ofAdvances in pharmacological and pharmaceutical sciences · 2023Article
- Essential Oils in the Treatment of Various Types of Acne-A Review.Plants (Basel, Switzerland) · 2022Review
- An Up-To-Date Review Regarding Cutaneous Benefits ofAntibiotics (Basel, Switzerland) · 2022Review
- Antimicrobial activity, in vitro anticancer effect (MCF-7 breast cancer cell line), antiangiogenic and immunomodulatory potentials of Populus nigra L. buds extract.BMC complementary medicine and therapies · 2022Article
- Evaluation of Wound Healing and Antibacterial Activities of Solvent Fractions of 80% Methanol Leaf Extract ofInfection and drug resistance · 2022Article
- The Risk of Emerging Resistance to Trimethoprim/Sulfamethoxazole inInfection and drug resistance · 2022Article
- Alkaloid profiling and antimicrobial activities of Papaver glaucum and P. decaisnei.BMC research notes · 2021Article
- Intake of Antioxidant Vitamins and Minerals in Relation to Body Composition, Skin Hydration and Lubrication in Young Women.Antioxidants (Basel, Switzerland) · 2021Article
- First insights into molecular basis identification of 16 s ribosomal RNA gene of Staphylococcus aureus isolated from Sudan.BMC research notes · 2021Article
- Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris.Pharmaceutics · 2021Article
- An Overview of the Biological Activity of Pyrrolo[3,4-Pharmaceuticals (Basel, Switzerland) · 2021Review
- A Unique Acylated Flavonol Glycoside fromAntioxidants (Basel, Switzerland) · 2021Article
- Atrial Natriuretic Peptide Affects Skin CommensalMicroorganisms · 2021Article
- Essential Oils as Natural Sources of Fragrance Compounds for Cosmetics and Cosmeceuticals.Molecules (Basel, Switzerland) · 2021Review
- The Inhibitory Efficiencies of Geraniol as an Anti-Inflammatory, Antioxidant, and Antibacterial, Natural Agent Against Methicillin-ResistantInfection and drug resistance · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcne is a frequent adolescent disease characterized by inflammatory and non-inflammatory lesions whose topical treatment very often presents adverse phenomena such as irritation or resistance to antibiotics that reduce the patient's compliance. The purpose of this study is to compare a commercial product (Acnatac gel) based on clindamycin-tretinoin (CTG) with a galenic compound containing 2 essential oils (
methodsSixty volunteers were randomly divided into an A group using MOTC and a B group, as a positive control, using CTG. The effectiveness was assessed with non-invasive skin analysis (Sebumeter, pH meter, Tewameter and Mexameter) and the counts of the number of lesions, after 15 and 30 days.
resultsIn both groups, there is a worsening of transepidermal water loss (TEWL) due to tretinoin. MOTC has improved, starting from 15 days of treatment, the papular erythema (p = 0.0329 vs CTG) and has reduced at all times even the rashes of retinoids present in the healthy perilesional skin (p = 0.0329 and p = 0.0017, respectively, at 15 and 30 days).
conclusionMOTC has shown, compared to Acnatac, to have anti-acne efficacy and to possess an anti-inflammatory activity, due to essential oils, able to reduce in vivo erythematous lesions and those induced by retinoids.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.