Evidence map›Paper›PMID 32210336›Full record

ArticleScientific reports2020

Isotopic Nitrogen-15 Labeling of Mice Identified Long-lived Proteins of the Renal Basement Membranes.

Pan Liu, Xinfang Xie, Jing Jin

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Urinary metabolome dynamics inMetabolomics : Official journal of the Metabolomic Society · 2025
    Article
  4. Basement membrane structure and function: Relating biology to mechanics.Matrix biology : journal of the International Society for Matrix Biology · 2025
    Review
  5. Basement membranes at a glance.Journal of cell science · 2025
    Review
  6. The life cycle of type IV collagen.Matrix biology : journal of the International Society for Matrix Biology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Peroxidasin is required for full viability in development and for maintenance of tissue mechanics in adults.Matrix biology : journal of the International Society for Matrix Biology · 2024
    Article
  11. Article
  12. Peptide location fingerprinting identifies structural alterations within basement membrane components in ageing kidney.Matrix biology : journal of the International Society for Matrix Biology · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Peroxidasin-mediated bromine enrichment of basement membranes.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Pan LiuFeinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Xinfang XieFeinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Jing JinFeinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. jing.jin@northwestern.edu.
Renal Research Institute · USNorthwestern University · US

Funding

Therapeutics Development Core (Core B)P30DK114857 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GEORGE, ALFRED L., QUAGGIN, SUSAN E. · 2018 to 2022
$5.7M
A Master Role of Symmetric Arginine Dimethylation in Lupus Autoantibody ResponseR21AI131087 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JIN, JING · 2018 to 2019
$435k
NIAID NIH HHS R21 AI131087NIDDK NIH HHS P30 DK114857
6 · The paper itself

Abstract

The kidney is comprised of highly complex structures that rely on self-maintenance for their functions, and tissue repair and regeneration in renal diseases. We devised a proteomics assay to measure the turnover of individual proteins in mouse kidney. Mice were metabolically labeled with a specially formulated chow containing nitrogen-15 (

Indexed as

AnimalsBasement MembraneExtracellular Matrix ProteinsFemaleGlomerular Basement MembraneIsotope LabelingKidneyKidney DiseasesLamininMaleMass SpectrometryMiceMice, Inbred C57BLNitrogen IsotopesProtein StabilityProteomicsExtracellular Matrix ProteinsLamininNitrogen-15Nitrogen Isotopes

Identifiers

PMID32210336
PMCPMC7093503
OpenAlexW3014053519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.